头像
陈增萍

发布于:暂无信息 点击数:4295

暂无信息

基本信息

教授,博士生导师

Email: zpchen@hnu.edu.cn

blob.png

教育背景

2002.10-2008.11  英国钮卡斯尔大学化工与先进材料学院,博士后。

1998.09-2001.05  湖南大学化学化工学院,理学博士;

1995.09-1998.06  湖南大学化学化工学院,理学硕士;

1991.09-1995.06  湖南大学化学化工学院,理学学士;


工作履历

2008.12- 现在     湖南大学化学化工学院,教授、博士生导师。

2001.06- 2002.09  湖南大学化学化工学院,讲师。


学术兼职

英国斯特斯克莱德大学(University of Strathclyde)纯粹与应用化学系荣誉教师

研究领域

目前主要从事复杂体系波谱定量分析理论和应用方面的研究,研究内容主要包括:复杂生物体系荧光光谱和质谱定量分析技术、表面增强拉曼光谱定量分析基础理论与应用、化学计量学理论和方法

科研项目

1. 国家自然科学基金,基于分子探针技术的化学计量学定量分析理论及其应用研究,2018.1-2021.12。

2. 国家自然科学基金,非均相体系荧光化学生物传感技术中的化学计量学理论及应用研究2015.1-2018.12。

3. 国家自然科学基金,具有普适性的表面增强拉曼光谱定量分析技术的研究,2013.1-2016.12。

4. 国家自然科学基金,复杂多相体系拉曼光谱定量分析的化学计量学方法研究,2011.1-2013.12。

5科技部重大科学仪器设备开发专项子任务SHINERS粒子模型设计与理论研究,2011.9-2015.8。

6. 湖南省自然科学基金复杂非均相体系荧光化学生物传感定量分析理论及应用研究,2016.1-2017.12

7. 教育部博士点基金(博导类)复杂非均相体系原位光谱定量分析基础理论研究,2014.1-2016.12。

8. 教育部新世纪人才计划化学计量学,2013.1-2014.12

学术成果

主要科研论文:

  1. Shi, C.X.; Chen, Z.P.*; Chen, Y.; Liu, Q.; Yu, R.Q. Quantification of dopamine in biological samples by surface-enhanced Raman spectroscopy: comparison of different calibration models, Chemometrics and Intelligent Laboratory Systems, 2017, 169, 87-93

  2. Zuo, Q.; Xiong, S.; Chen, Z.P.*; Chen, Y.; Yu, R.Q. A novel calibration strategy based on background correction for quantitative circular dichroism spectroscopy, Talanta, 2017, 174, 320-324

  3. Kong, J.J.; Chen, Z.P.*; Chen, Y.; Yan, X.F.; Yu, R.Q. Direct DNA quantification in cell lysates by fluorometric method in combination with an advanced chemometric model, Chemometrics and Intelligent Laboratory Systems, 2016, 151, 9-14

  4. Hu, Y.L.; Chen, Z.P.*; Chen, Y.; Shi, C.X.; Yu, R.Q. Generalized multiple internal standard method for quantitative liquid chromatography mass spectrometry, Journal of Chromatography A, 2016, 1445, 112-117

  5. Yan, X.F.; Chen, Z.P.*; Cui, Y.Y.; Hu, Y.L.; Yu, R.Q. Quantitative generalized ratiometric fluorescence spectroscopy for turbid media based on probe encapsulated by biologically localized embedding, Analytica Chimica Acta, 2016, 921, 38-45

  6. Chen, Y.; Chen, Z.P.*; Zuo, Q.; Shi, C.X.; Yu, R.Q. Surface-enhanced Raman spectroscopy based on conical holed enhancing substrates, Analytica Chimica Acta, 2015, 887, 45-50

  7. Yan, X.F.; Chen, Z.P.*; Kong, J.J.; Hu, Y.L.; Chen, Y.; Yu, R.Q. Determination of free Mg2+ in turbid samples with the coexistence of interfering Ca2+ using extended quantitative fluorescence model, Chemometrics and Intelligent Laboratory Systems, 2015, 147, 41-46

  8. Shi, C.X.; Chen, Z.P.*; Chen, Y.; Yu, R.Q. Quantitative analysis of hormones in cosmetics by LC-MS/MS combined with an advanced calibration model, Analytical Methods, 2015, 7, 6804-6809

  9. Long, S.Y.; Chen, Z.P.*; Chen, Y.; Yu, R.Q. Quantitative detection of captopril in tablet and blood plasma samples by the combination of surface-enhanced Raman spectroscopy with multiplicative effects model, Journal of Raman Spectroscopy, 2015, 46, 605-609

  10. Chen, Y.; Chen, Z.P.*; Jin, J.W.; Yu, R.Q. Quantitative determination of ametryn in river water using surface-enhanced Raman spectroscopy coupled with an advanced chemometric model, Chemometrics and Intelligent Laboratory Systems, 2015, 142, 166-171

  11. Chen, Y.; Chen, Z.P.*; Long, S.Y.; Yu, R.Q. Generalized ratiometric indicator based surface-enhanced Raman spectroscopy for the detection of Cd2+ in environmental water samples, Analytical Chemistry, 2014, 86, 12236-12242

  12. Du, H.L.; Chen, Z.P.*; Song, M.; Chen, Y.; Yu, R.Q. Novel calibration model maintenance strategy for solving the signal instability in quantitative liquid chromatography–mass spectrometry, Journal of Chromatography A, 2014, 1338, 44-50

  13. Jin, J.W.; Chen, Z.P.*; Song, J.; Xia, T.H.; Yu, R.Q. Determination of glucose in plasma by dry film-based near infrared spectroscopy: correcting the thickness variations of dry films without applying an internal standard, Chemometrics and Intelligent Laboratory Systems, 2014, 135, 63-69

  14. Song, M.; Chen, Z.P.*; Chen, Y.; Jin, J.W. Multiplicative effects model with internal standard in mobile phase for quantitative liquid chromatography-mass spectrometry, Talanta, 2014, 125, 347-351.

  15. Xia, T.H.; Chen, Z.P.*; Chen, Y.; Jin J.W.; Yu, R.Q. Improving the quantitative accuracy of surface enhanced Raman spectroscopy by the combination of microfluidics with a multiplicative effects model, Analytical Methods, 2014, 6, 2363-2370

  16. Song, J.; Chen, Z.P.*; Jin, J.W.; Chen, Y.; Yu, R.Q. Quantitative surface-enhanced Raman spectroscopy based on the combination of magnetic nanoparticles with an advanced chemometric model, Chemometrics and Intelligent Laboratory Systems, 2014, 135, 31-36

  17. Chen, Y.; Chen, Z.P.*; Yang J.; Jin, J.W.; Zhang, J.; Yu, R.Q. Quantitative fluorescence spectroscopy in turbid media: a practical solution to the problem of scattering and absorption, Analytical Chemistry, 2013, 85, 2015-2020

  18. Yang, J.; Chen, Z.P.*; Zhang, J.; Jin, J.W.; Chen, Y. Quantitative Raman spectrometry: the accurate determination of analytes in solution phase of turbid media, Chemometrics and Intelligent Laboratory Systems, 2013, 126, 6-10

  19. Zhang, J.; Liu S.Z.; Yang, J.; Song, M.; Song, J.; Du, H.L.; Chen, Z.P.* Quantitative spectroscopic analysis of heterogeneous systems: chemometric methods for the correction of multiplicative light scattering effects, Review in Analytical Chemistry , 2013, 32(2), 113-125

  20. Chen, Z.P*; Li, L.M.; Jin, J.W.; Nordon, A.; Littlejohn, D.; Yang, J.; Zhang, J.; Yu, R.Q. Quantitative analysis of powder mixtures by Raman spectrometry: the influence of particle size and its correction, Analytical Chemistry, 2012, 84, 4088-4094

  21. Jin, J.W.; Chen, Z.P.*; Li, L.M.; Steponavicius, R.; Thennadil, S.N.; Yang, J.; Yu, R.Q. Quantitative spectroscopic analysis of heterogeneous mixtures: the correction of multiplicative effects caused by variations in physical properties of samples, Analytical Chemistry, 2012, 84, 320-326

  22. Chen Z.P.*; Zhong L.J.; Nordon A.; Littlejohn D.; Holden M.; Fazenda M.; Harvey L.; McNeil B.; O’Kennedy R. Calibration of multiplexed fibre-optic spectroscopy, Analytical Chemistry, 2011, 83, 2655-2659

  23. Chen Z.P.*; Li L.M.; Yu R.Q.; Littlejohn D.; Nordon A.; Morris J.; Dann A.S.; Jeffkins P.A.; Richardson M.D.; Stimpson S.L. Systematic prediction error correction: a novel strategy for maintaining the predictive abilities of multivariate calibration models, Analyst, 2011, 136, 98-106

  24. Chen Z.P.; Lovett D.; Morris J. Process analytical technologies and real time process control a review of some spectroscopic issues and challenges, Journal Process Control, 2011, 21, 1467-1482

  25. Du W.; Chen Z.P.*; Zhong L.J.; Wang S.X.; Yu R.Q.; Nordon A.; Littlejohn D.; Holden M. Maintaining the predictive abilities of multivariate calibration models by spectral space transformation, Analytica Chimica Acta, 2011, 690, 64-70

  26. Chen, Z.P.*; Morris, J. Borissova, A.; Khan, S.; Mahmud, T.; Penchev, R.; Roberts, K. On-line monitoring of batch cooling crystallisation of organic compounds using ATR-FTIR spectroscopy coupled with an advanced chemometric calibration method, Chemometrics and Intelligent Laboratory Systems, 2009, 96, 49-58

  27. Chen, Z.P.; Morris, J. Process analytical technology and compensating for nonlinear effects in process spectroscopic data for improved process monitoring and control, Biotechnology Journal, 2009, 4, 610-619

  28. Chen, Z.P.*; Fevotte, G.; Caillet, A.; Littlejohn, D.; Morris, J. Advanced calibration strategy for in-situ quantitative monitoring of phase transition processes in suspensions using FT-Raman spectroscopy, Analytical Chemistry, 2008, 80, 6658-6665

  29. Chen, Z.P.*; Morris, J. Improving the linearity of spectroscopic data subjected to fluctuations in external variables by the extended loading space standardization, Analyst, 2008, 133, 914-922

  30. Chen, Z.P.; Lovett, D.; Morris, J. Process analytical technologies (PAT)-the impact for process systems engineering, Computer Aided Chemical Engineering, 2008, 25, 967-972

  31. Chen, Z.P.; Morris, J.; Martin, E. Extracting chemical information from spectral data with multiplicative light scattering effects by optical path-length estimation and correction, Analytical Chemistry, 2006, 78, 7674-7681

  32. Chen, Z.P.; Morris, J.; Martin, E. Correction of temperature-induced spectral variations by loading space standardization, Analytical Chemistry, 2005, 77, 1376-1384

  33. Chen, Z.P.; Morris, J.; Martin, E.; Hammond, R.B.; Lai, X.J.; Ma, C.Y.; Purba, E.; Roberts, K.J.; Bytheway, R. Enhancing the signal-to-noise ratio of X-ray diffraction profiles by smoothed principal component analysis, Analytical Chemistry, 2005, 77, 6563-6570

  34. Chen, Z.P.; Morris, J.; Martin, E.; Yu, R.Q.; Liang, Y.Z.; Gong, F. Recursive evolving spectral projection for revealing the concentration windows of overlapping peaks in two-way chromatographic experiments, Chemometrics and Intelligent Laboratory Systems, 2004, 72, 9-19

  35. Chen, Z.P.; Yu, R.Q. Mitigating model deficiency in three-way data analysis by the combination of background constraining and iterative correcting techniques, Analytica Chimica Acta, 2003, 487, 171-180

  36. Chen, Z.P.; Wu, H.L.; Li, Y.; Yu, R.Q. On self-weighted alternating trilinear decomposition algorithm-the property of being insensitive to the excess factors used in calculation, Journal of Chemometrics, 2001, 15, 427-438

  37. Chen, Z.P.; Li, Y.; Yu, R.Q. Pseudo alternating least squares algorithm for trilinear decomposition, Journal of Chemometrics, 2001, 15, 149-167

  38. Chen, Z.P.; Liu, Z. Cao, Y. Z.; Yu, R.Q. Efficient way to estimate the optimum number of factors for trilinear decomposition, Analytica Chimica Acta, 2001, 444, 295-307

  39. Chen, Z.P.; Wu, H.L.; Jiang, J.H.; Li, Y.; Yu, R.Q. A novel trilinear decomposition algorithm for second orders linear calibration, Chemometrics and Intelligent Laboratory Systems, 2000, 52, 75-86

  40. Chen, Z.P.; Wu, H.L.; Li, Y.; Yu, R.Q. Novel constrained PARAFAC algorithm for second order linear calibration, Analytica Chimica Acta, 2000, 423, 187-196

  41. Chen, Z.P.; Jiang, J.H.; Li, Y.; Liang, Y.Z.; Yu, R.Q. Fuzzy linear discriminant analysis for chemical data sets, Chemometrics and Intelligent Laboratory Systems, 1999, 45, 295-302

  42. Chen, Z.P.; Jiang, J.H.; Li, Y.; Yu, R.Q. Non-linear mapping using real-valued genetic algorithm, Chemometrics and Intelligent Laboratory Systems, 1999, 45, 409-418

  43. Chen, Z.P.; Liang, Y.Z.; Jiang, J.H.; Li, Y.; Qian, J.Y.; Yu, R.Q. Determination of the number of components in mixtures using a new approach incorporating chemical information, Journal of Chemometrics, 1999, 13, 15-30

  44.  Chen, Z.P.; Jiang, J.H.; Li, Y.; Shen, H.L.; Liang, Y.Z.; Yu, R.Q. Smoothed window factor analysis, Analytica Chimica Acta, 1999, 381, 233-246

     

发明专利:

  1. 陈增萍、俞汝勤. 用于维护复杂体系光谱校正模型预测能力的方法, 中国发明专利, 专利号:ZL201210243634.02012.05.23

  2. 陈增萍、金竞文、俞汝勤. 用于复杂非均相混合物体系的准确光谱定量分析方法,中国发明专利, 专利号:ZL201110280639.62013.09.04

  3. 陈增萍、李丽梅、金竞文. 一种粉末混合物的拉曼光谱准确定量分析方法,中国发明专利, 专利号:ZL201110409685.1(2013.11.20)

  4. 陈增萍、金竞文、俞汝勤. 具有普适性的表面增强拉曼光谱定量分析技术,中国发明专利, 专利号:ZL201210243634.0(2014.04.16)

  5. 陈增萍,陈瑶,田中群. 一种环境水体样本中镉离子含量的定量分析方法,专利号:ZL201410439838.02016.06.08

  6. 陈增萍,陈瑶,田中群. 一种增强SERS信号的方法及其应用,中国发明专利, 专利号:ZL201510002031.52017.08.04


奖励与荣誉

曾获湖南省2002自然科学技术一等奖