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何凤姣

发布于:2018-06-26 星期二 12:41:30 点击数:5204

   何凤姣,湖南大学化学化工学院教授,国务院政府特殊津贴专家,科技部创新创业人才,全国妇联执委,湖南省政协委员。发明了高耐磨性、高耐蚀性、环保型钨合金电镀技术,2011年获国家技术发明二等奖。该项目被列为2012年国家经信委推广的清洁生产工艺,已用于含有高硫化氢、二氧化碳、高矿化度的西南油气田和塔里木油田,获得好的效果。在微生物快速检测领域,主持研制开发了临床医疗急需的血培养仪,该仪器的研发,对我国提高诊疗水平,防止抗生素的滥用,具有重要意义。相关研究获2017年获湖南省自然科学一等奖。


基本信息

姓名:何凤姣
性别:
出生年月:1964年8月
职称:二级教
最高学历及毕业时间:博士,1994年
工作单位:湖南大学化学化工学院,化学生物传感与计量学国家重点实验室
通讯地址:湖南大学化学化工学院
邮箱: fengjiaohe@hnu.edu.cn 
手机:13787799232

教育背景

1982.9-1986.7, 湖南大学化学化工学院, 分析化学本科

1986.9-1989.6, 湖南大学化学化工学院, 分析化学硕士

1991.9-1994.12,湖南大学化学化工学院, 分析化学博士

1997.1-1997.11  美国阿拉巴马大学医学院  博士后

1997.12-1998.12 美国加州大学洛杉矶分校  博士后



工作履历


1989.6-1991.8, 湘潭机电专科学校,  教师

1995.1-1996.12,湖南大学国际商学院,副教授

1999---至今,湖南大学化学化工学院, 教授


学术兼职

湖南省预防医学会卫生检验专业委员会副主任

湖南省环境保护厅特约环保监察员

研究领域

1.细菌、病毒传感器的研制与应用
利用压电传感原理,结合纳米技术、分子导线、表面修饰、叉指电极等,构建微生物快速检测系统,进行细菌、病毒的生长和代谢研究,开发出实用的检测方法和检测设备。
2.金属表面处理方法与应用研究
研究新的金属表面处理工艺及表面处理的废水零排放,废酸的回收循环利用,新型镀层表观形貌、结构的表征及相关性质的研究,侧重在制造领域表面处理及应用研究。

科研项目

1.国家自然科学基金仪器专项,20227502,压电生化传感仪,80万元

2.国家高技术研究发展计划(863计划),2013AA020203,基于荧光检测技术的自动化临床微生物检测分析仪器研制,80万

3.国家自然科学基金面上项目,21275042,基于核酸适配体的结核杆菌电化学传感器的研制与应用,80万

4.国家自然科学基金面上项目,20575018,分子导线压电微生物传感新技术理论与应用,26万元
5.国家自然科学基金面上项目,20875026,结核杆菌压电测试新技术研究与应用,36万元
6.国家科技支撑计划,有毒有害元素替代技术,85万元
7.钨合金表面处理工艺研究,湖南省重点计划,20万元


学术成果

授权专利

授权发明专利20项,授权实用新型专利3项。

成果转化

研制的血培养仪已获生产许可证和产品注册证书;
研制的电镀钨合金代镀铬,获得国家环保总局环境保护A类推广证书国家重点新产品证书,被国家发改委评为260项实用环保技术之一,2008年列入无锡市政府530A类计划。

教材:无机化学,科学出版社,被评为国家十一五教材

发表论文:

[1]XiaoQing Zhang, Ye Feng, QiongQiong Yao, Fengjiao He*,Selection of a new Mycobacterium tuberculosis H37Rv aptamer and its application in the construction of a SWCNT/aptamer/Au-IDE MSPQC H37Rv sensor,Biosensors and Bioelectronics,98 (2017) 261–26

[2]Xiaohong Shi, Xiaoqing Zhang, Qiongqiong Yao, Fengjiao He*,A novel method for the rapid detection of microbes in blood using pleurocidin antimicrobial peptide functionalized piezoelectric sensor,Journal of Microbiological Methods 133 (2017) 69–75

[3]Fengjiao He*, Yunchang Xiong, Jing Liu, Feifei Tong, Danyang Yan,Construction of Au-IDE/CFP10-ESAT6 aptamer/DNA-AuNPs MSPQC for rapid detection of Mycobacterium tuberculosis,Biosensors and Bioelectronics 77 (2016) 799–804

[4]Yan Lian, Fengjiao He*, Huan Wang, Feifei Tong,A new aptamer/graphene interdigitated gold electrode piezoelectric
sensor for rapid and specific detection of Staphylococcus aureus,Biosensors and Bioelectronics 65 (2015) 314–319

[5]Feifei Tong, Yan Lian, Fengjiao He*,Novel S-MSPQC cell sensor for real time monitoring the injury of endothelial cell by LPS and assessing the drug effect on this injury,Biosensors and Bioelectronics 71 (2015) 62–67

[6]Fengjiao He*,Danyang Yan,Construction and Application of a Novel Impedance Sensor for Siderophore,Analytical Letters, 48:2, 259-268

[7]Feifei Tong, Yan Lian, Huang Zhou, Xiaohong Shi, and Fengjiao He*,Multichannel Series Piezoelectric Quartz Crystal Cell Sensor for Real Time and Quantitative Monitoring of the Living Cell and Assessment of Cytotoxicity,Anal. Chem. 2014, 86, 10415-10421

[8]Yan Lian, Fengjiao He ∗, Xianwen Mi, Feifei Tong, Xiaohong Shi,Lysozyme aptamer biosensor based on electron transfer from SWCNTs to SPQC-IDE,Sensors and Actuators B 199 (2014) 377–383

[9]Xianwen Mi, Fengjiao He∗, Meiyu Xiang, Yan Lian, Songlin Yi,Novel phage-piezoelectric sensor for rapid drug susceptibility testing of Mycobacterium tuberculosis,Sensors and Actuators B 193 (2014) 715–722

[10]Xiaohong Shi, Fengjiao He ∗, Yan Lian, Danyang Yan, Xiaoqing Zhang,A new aptamer/SWNTs IDE-SPQC sensor for rapid and specific detection of Group A Streptococcus,Sensors and Actuators B 198 (2014) 431–437

[11]F.J. He*, Y.Z. Fang, S.J. Jin,The study of corrosion–wear mechanism of Ni–W–P alloy,Wear 311 (2014) 14–20

[12]Xianwen Mi,Fengjiao He,*,Meiyu Xiang, Yan Lian, and Songlin Yi,Novel Phage Amplified Multichannel Series Piezoelectric Quartz Crystal Sensor for Rapid and Sensitive Detection of Mycobacterium tuberculosis,Anal. Chem. 2012, 84, 939-946

[13]Fengjiao He*, Meiyu Xiang, and Xianwen Mi,A NEW BACTERIOPHAGE-MODIFIED PIEZOELECTRIC SENSOR FOR RAPID AND SPECIFIC DETECTION OF MYCOBACTERIUM,Analytical Letters, 45: 1–12, 2012

[14]Fengjiao He,* Suzhen Chen and Lingling Zhang,The construction and application of a molecular wire piezoelectric
urease-producing bacteria sensor,Anal. Methods, 2012, 4, 2145

[15]Fengjiao He ⁎, Hui Su, Hui Ju, Ling Tan, Que Zhou,A new blackening process for NiWP alloy deposits,Surface & Coatings Technology 213 (2012) 133–138

[16]Fengjiao He, Li Lin, and Jiandang Zhou, Multi-Channel Series Piezoelectric Quartz Crystal Sensor with Partial Least Square Method for Identification of Clinically Relevant Bacteria, Sensor Lett. 9, 472-478 (2011)

[17]Ren J L, He F J, Zhang L L. The construction and application of a new PPY-MSPQC for l-asparaginase activity assay. Sensors and Actuators B: Chemical, 2010, 145:272-277
[18]He F J, Zhong M. New MSPQC-PLS method for the early clinic identification of commonly encountered Candida species. Talanta, 2010, 80 (3): 1210-1215
[19]He F J, Tu J R. New Medium for Rapid Quantification of Micrococcus Luteus Cells byMultic hannel Series Piezoelectric Quartz Crystal Based Method. Sensor letters, 2010, 8: 1-5
[20]He F J, Li T, Zhang L L, Yuan H, Zhou J D. New MSPQC Method for Rapid Identification and Quantification of Pseudomonas aeruginosa. Analytical Letters, 2009, 42(1): 58-67
[21]Su C W, Wang E L, Zhang Y B, He F J. Ni1−xFex (0.1 < x < 0.75) alloy foils prepared from a fluorborate bath using electrochemical deposition. Journal of Alloys and Compounds, 2009,474: 190-194
[22]Su C W, He F J, Ju H, Zhang Y B, Wang E L. Electrodeposition of Ni, Fe and Ni–Fe alloys on a 316 stainless steel surface in a fluorborate bath. Electrochimica Acta, 2009, 54: 6257-6263
[23]Ren J L, He F J, Yi S L, Cui X Y. A new MSPQC for rapid growth and detection of Mycobacterium tuberculosis. Biosensors and Bioelectronics, 2008, 24(3): 403-409
[24]He F J, Ren J L, Liu Z H. The study and application of a new IDE–PQC sensor. Sensors and Actuators B: Chemical, 2007, 123(2): 1057-1063
[25]Ren J L, He F J, Zhang L L, Su C W, Liu Z H. A new B-PAn-P system for the detection of bacteria population. Sensors and Actuators B: Chemical, 2007, 125: 510-516
[26]He F J, Zhou J. A new antimicrobial susceptibility testing method of Escherichia coli against ampicillin by MSPQC. Journal of Microbiology Methods, 2007, 68(3): 563-567
[27]He F J, Zhang X Q, Zhou J D, Liu Z H. A new MSPQC system for rapid detection of pathogens in clinical samples. Journal of Microbiology Methods, 2006, 66(1): 56-62
[28]He F J, Zhang X Q, Liu Z H. A new sensor method for studying the effect of surfactants on the growth of Pseudomonas aeruginosa. Sensors and Actuators B: Chemical, 2006, 113(1): 428-434



奖励与荣誉

2017年,湖南省自然科学一等奖

2016年,国务院特殊津贴

2013年,湖南省十大同心人物

2012,入选国家创新创业人才

2011年,国家科技发明一等奖

2009年获第四届中国技术市场协会金桥奖优秀项目奖;
2007年获中国机械工业科学技术一等奖,湖南省科技进步二等奖;