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杨文

发布于:2018-01-15 星期一 16:51:39 点击数:8398

副教授 / 博士生导师(有机化学)

电子邮件:yangwen@hnu.edu.cn     QQ330133808

实验室:有机楼/药厂403          办公室:有机楼/药厂409


基本信息

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男,1984年出生,江西南昌人。2008年本科毕业于陕西师范大学,2014年于北京理工大学获博士学位(导师:杜大明教授)。20146月至20168月于香港科技大学从事博士后研究(合作导师:孙建伟教授)。20169月被聘为湖南大学化学化工学院副教授,研究方向为有机合成方法学,主要从事不对称催化反应研究,已在Angew. Chem., Int. Ed.Chem. Sci.、Org. Lett.Chem. Commun.等重要国际期刊上以第一或通讯作者发表SCI论文20余篇,引用1000多次,H指数达17;获中国发明专利1项。


教育背景

2008.09-2014.03        北京理工大学        工学博士

2004.09-2008.07          陕西师范大学          理学学士



工作履历

2016.09-现在                湖南大学 化学化工学院           副教授、博士生导师

2014.06-2016.08        香港科技大学 化学系    博士后



研究领域

1)设计合成新型有机小分子催化剂和手性配体,发展高效不对称催化合成方法

2开发催化合成方法应用于有机染料的制备


科研项目

国家自然科学基金青年基金,项目编号:21702055,2018-2020.

湖南大学科研启动经费,项目编号:531107050885, 2016-2020.


学术成果

18. Zhang, W.; Yang, W.*; Zhao, W.* Lewis Acid-Mediated Electrophilic Cyanation of 2,2'-Biphenols. J. Org. Chem. 2020, 85, 8702-8713.

17. Wang, W.; Xiong, W.; Wang, J.*; Wang, Q.-A.*Yang, W.* Brønsted Acid-Catalyzed Asymmetric Friedel–Crafts Alkylation of Indoles with Benzothiazole-Bearing Trifluoromethyl Ketone Hydrates. J. Org. Chem. 202085, 4398-4407.

16.  Dong, W.; Yang, H.;Yang, W.*; Zhao, W.* Rhodium-Catalyzed Remote Isomerization of Alkenyl Alcohols to Ketones. Org. Lett. 2020, 22, 1265-1269.

15.  Sun, G.; Zou, X.; Wang, J.*; Yang, W.Sulfur-directed palladium-catalyzed C(sp3)-H α-arylation of 3-pyrrolines: easy access to diverse polysubstituted pyrrolidines. Org. Chem. Front. 2020, 7, 666-671.

14. Zou, X.;  Sun, G.; Huang, H.; Wang, J.*; Yang, W.*; Sun, J.* Catalytic Enantioselective Synthesis of 1,4-Benzodioxepines. Org. Lett. 2020, 22, 249-252.

13.  Huang, H.; Yang, W. (co-first author); Chen, Z. (co-first author); Lai, Z.; Sun, J.* A mild catalytic synthesis of 2-oxazolines via oxetane ring-opening: rapid access to a diverse family of natural products. Chem. Sci. 2019, 10, 9586-9590.

12.  Xiong, W.; Li, S.; Fu, B.; Wang, J.*; Wang, Q.-A.*; Yang, W.* Visible-Light Induction/Brønsted Acid Catalysis in Relay for the Enantioselective Synthesis of Tetrahydroquinolines. Org. Lett. 2019, 21, 4173-4176.

11.  Yang, W.; Ma, D. (co-first author); Zhou, Y.; Dong, X.; Lin, Z.;*  Sun, J.* NHC-Catalyzed Electrophilic Trifluoromethylation: Efficient Synthesis of γ-Trifluoromethyl         Unsaturated Esters. Angew. Chem., Int. Ed. 201857, 12097-12101.

10.  Yang, W.; Hu, W.; Dong, X.; Li, X.; Sun, J.* N-Heterocyclic Carbene Catalyzed γ-Dihalomethylenation of Enals by Single-Electron Transfer.  Angew. Chem., Int. Ed. 2016, 55, 15783-15786.

9.    Yang, W.; Wang, Z.; Sun, J.* Enantioselective Oxetane Ring Opening with Chloride: Unusual Use of Wet Molecular Sieves for the Controlled Release of HCl. Angew. Chem., Int. Ed. 2016, 55, 6954-6958.

8.    Yang, W.; Sun, J.*Organocatalytic Enantioselective Synthesis of 1,4-Dioxanes and Other Oxa- Heterocycles by Oxetane Desymmetrization. Angew. Chem., Int. Ed. 2016, 55, 1868-1871.

7.    Dong, X.; Yang, W.; Hu, W.; Sun, J.* N-Heterocyclic Carbene Catalyzed Enantioselective α-Fluorination of Aliphatic Aldehydes and α-Chloro Aldehydes: Synthesis of α-Fluoro Esters, Amides, and Thioesters. Angew. Chem., Int. Ed. 201554, 660-663.

6.    Yang, W.; He, H.-X.; Gao, Y.; Du, D.-M.* Organocatalytic Cascade Aza-Michael/Michael Addition Reactions for Enantioselective Synthesis of Functionalized Tetrahydroquinolines and Tetrahydrochromano- quinolines. Adv. Synth. Catal. 2013, 355, 3670-3678.

5.    Yang, W.; Yang, Y.; Du, D.-M.* Squaramide-Tertiary Amine Catalyzed Asymmetric Cascade Sulfa- Michael/Michael Addition via Dynamic Kinetic Resolution: Access to Highly Functionalized Chromans with Three Contiguous Stereocenters. Org. Lett. 2013, 15, 1190-1193.

4.    Yang, W.; Du, D.-M.* Squaramide-Catalyzed Cascade Aza-Michael/Michael Addition: Enantioselective Construction of Functionalized Spirooxindole Tetrahydroquinolines. Chem. Commun. 2013, 49, 8842-8844.

3.    Yang, W.; Du, D.-M.* Chiral Squaramide-Catalyzed Highly Diastereo- and Enantioselective Direct Michael Addition of Nitroalkanes to Nitroalkenes. Chem. Commun. 2011, 47, 12706-12708.

2.    Yang, W.; Du, D.-M.* Chiral Squaramide-Catalyzed Highly Enantioselective Michael Addition of 2-Hydroxy-1,4-naphthoquinones to Nitroalkenes. Adv. Synth. Catal. 2011, 353, 1241-1246.

1.  Yang, W.; Du, D.-M.* Highly Enantioselective Michael Addition of Nitroalkanes to Chalcones Using Chiral Squaramides as Hydrogen Bonding Organocatalysts. Org. Lett. 2010, 12, 5450-5453.