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聂和民

发布于:2018-10-18 星期四 09:50:36 点击数:11878

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聂和民

教授、博士生导师、湖南省杰青、岳麓学者、生物纳米与组织工程学研究所责任教授

Tel: 13974863930

E-mail: niehemin@hnu.edu.cn    niehemin@u.nus.edu


基本信息

聂和民,2009年获新加坡国立大学化学与生物分子工程博士学位,2010-2012年在纽约哥伦比亚大学医学中心从事博士后研究,2012年被聘为湖南大学教授、博士生导师。2013年起担任中国生物医学工程学会组织工程与再生医学分会理事会青年委员,2015年获得“湖南省自然科学杰出青年基金”,2017年入选“湖南大学岳麓学者奖励计划”,2017年起担任《Current Smart Materials》编委、湖南省生物材料学会理事、湖南省及长沙市医疗器械行业协会专家,2019年起担任中国医学装备协会转化医学分会委员。长期致力于生物材料、干细胞、组织再生与肿瘤治疗领域的研究工作,主持国家自然科学基金2项、湖南省重点研发计划项目2项、长沙市重点研发计划项目1项,获甘肃省科技进步二等奖,以第一或通讯作者在Advanced Drug Delivery Reviews、Biomaterials、Journal of Controlled Release、ACS Applied Materials & Interfaces、Biotechnology and Bioengineering等杂志上发表了20余篇论文【引用次数超过1000,H-index=15, i10-index=17】,参与了五本英文学术专著的编纂工作,并承担多个英文SCI期刊的审稿工作。


Prof. Nie received his PhD from the National University of Singapore (with Prof. Chi-Hwa Wang) in 2009. He had worked at Columbia University in the City of New York as a Postdoctoral Research Scientist (with Prof. Jeremy J. Mao) before joining Hunan University in 2012 as a full professor (Yuelu Scholar). He currently serves as  director of Bionanotechnology and Tissue Engineering Institute of HNU. He was elected as a senior member for the Chinese Society of Biomedical Engineering (CSBME) in 2013, and has since served as a youth committee member in the branch of Tissue Engineering and Regenerative Medicine. His current research interest includes biomaterials, controlled release, tumor therapy and regenerative medicine. Besides his publications in high-level journals, Prof. Nie is active in review works for various journals and has also participated in the preparation of 5 Biomedical Engineering books.


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Source: https://publons.com/researcher/1711779/hemin-nie

教育背景

2005-2009年  新加坡国立大学  化学与生物分子工程系  博士学位

工作履历

2012-至今   湖南大学  生物学院  教授、博士生导师

2010-2012  美国哥伦比亚大学  医学中心  博士后研究科学家(Postdoctorial Research Scientist)

2008-2010  新加坡国立大学  化学与生物分子工程系 研究员(Research Fellow) 

学术兼职

1、中国医学装备协会转化医学分会委员

2、中国生物医学工程学会组织工程与再生医学分会理事会青年委员

3、湖南省生物材料学会理事

4、湖南省神经学会理事

5、《Current Smart Materials》编委

6、湖南省及长沙市医疗器械行业协会专家

7、湖南省、广东省、厦门市创新创业项目评审技术专家

研究领域

本课题组的研究兴趣包括以下四方面:

1、利用生物材料构建细胞微环境(Engineering of cell niche)

2、组织修复(再生)以及可视化(Tissue regeneration and live imaging )

3、肿瘤发生、治疗以及可视化(Tumorigenesis, tumor therapy and live imaging)

      

本课题组招收硕士研究生、博士研究生及博士后,生物学、基础医学、高分子材料学背景的同学优先。欢迎有志于基础医学研究的同学加入课题组,一同致力于探究生命奥秘。

联系方式:niehemin@hnu.edu.cn 

                 niehemin@u.nus.edu 

办公室:湖南省长沙市岳麓区天马山路天马二街湖南大学生物学院新办公楼309


科研项目

1、湖南省重点研发计划项目,2020DK2001,2020/07-2022/06,主持人.

2、长沙市重点研发计划项目,kq1901024,2018/07-2021/06,主持人。

3、湖南省重点研发计划项目,2018SK2106,2018/01-2020/12,主持人。

4、国家自然科学基金面上项目,31670997,2017/01-2020/12,主持人。

5、深圳市科创委基础研究(自由探索)项目,JCYJ20160530193417959,2016/09-2018/08,主持人。

6、湖南省自然科学杰出青年基金,2015JJ1007,2015/01-2017/12,主持人。

7、国家自然科学基金青年基金项目,31200727,2013/01-2015/12,主持人。


学术成果

著作章节(Book chapters):

1.     Hemin Nie (*), Jeremy J. Mao (*), Micro-/nanotech-based craniofacial tissue engineering, Handbook of Intelligent Scaffolds for Tissue Engineering and Regenerative Medicine (2nd Edition), Gilson Khang, Pan Stanford Publishing, pp 660-675, United States, 2017.

2.     Hemin Nie, Jeremy J. Mao (*), Dental and craniofacial bioengineering, Tissue Engineering: Principles and Practices, John P Fisher, Antonios G Mikos, Joseph D Bronzino, Boca Raton : CRC Press, pp 28-1-28-17, United States, 2013.

3.     Hemin Nie, Jin Kim, Susan Y. Fu, Jeremy J. Mao (*), Biomaterials Selection for Dental Pulp Regeneration, Comprehensive Biomaterials, Paul Ducheyne, Kevin Healy, Dietmar Hutmacher, Elsevier, pp 245-254, United States, 2011.

论文(JCR一区 Q1):

【2013年-至今】

1.     Yujian Zou, Xiaohong Wen, Dan Ling, Dongshan Zhang, Lei Lei, Dan Zhu, Honghui Wang, Kemin Wang, Qiuping Guo (*), Hemin Nie (*), Precise monitoring of mesenchymal stem cell homing to injured kidney with an activatable aptamer probe generated by cell-SELEX. Applied Mateirals Today, 2021, 22, 100974.

2.     Bei Xie, Mengting Chen, Pinghui Ding, Xing Zhang, Dan Zhu, YUjian Zou, Zhili Deng, Guoming Sun (*), Ji Li (*), Hemin Nie (*), Induction of dermal fibroblasts into dermal papilla cell-like cells in hydrogel microcapsules for enhanced hair follicle regeneration. Applied Mateirals Today, 2020, 21, 100805.

3.     Lin Lan, Qiuping Guo, Hemin Nie, Chang Zou, Qingyun Cai, Jin Huang, Xiangxian Meng, Linear-hairpin variable primer RT-qPCR for MicroRNA. Chemical Science, 2019, 10, 2034-2043.

4.     Can Zhang, Bei Xie, Yujian Zou, Dan Zhu, Lei Lei (*), Dapeng Zhao (*), Hemin Nie (*), Zero-dimensional, one-dimensional, two-dimensional and three-dimensional biomaterials for cell fate regulation, Advanced Drug Delivery Reviews, 2018, 132, 33-56.

5.     Qian Li, Yun Bai, Tao jin, Shuo Wang, Wei Cui, Ilinca Stanciulescu, Rui Yang, Hemin Nie (*), Linshan Wang (*), Xing Zhang (*), Bioinspired engineering of poly(ethylene glycol) hydrogels and natural protein fibers for layered heart valve constructs, ACS Applied Materials & Interfaces, 2017, 9, 16524-16535.

6.     Bei Xie, Jipeng Yi, Jian Peng, Xing Zhang (*), Lei Lei, Dapeng Zhao, Zhixin Lei, Hemin Nie (*), Characterization of synergistic anti-tumor effects of doxorubicin and p53 via graphene oxide-polyethyleneimine nanocarriers, Journal of Materials Science & Technology, 2017, 44, 3372-3383.

7.     Tianmu Hu, Anwar Saeed Ahmed Qahtan, Lei Lei (*), Zhixin Lei, Dapeng Zhao, Hemin Nie (*), Inhibition of HeLa cell growth by doxorubicin-loaded and tuftsin-conjugated arginate-PEG microparticles, Bioactive Materials, 2017, 3, 48-54.

8.     Cuiping Zhong, Hongwei Shen, Yu Han, Shuo Wang, Ye Wang, Xining Xu, Jianhua Qiu, Hemin Nie (*), Alginate microcapsules co-embedded with MSCs and anti-EGF mAb for the induction of hair cell-like cells in guinea pigs by taking advantage of host EGF, Journal of Materials Chemistry B, 2016, 4, 7387-7397.

9.     Dapeng Zhao, Lei Lei, Shuo Wang, Hemin Nie (*), Understanding cell homing-based tissue engineering from the perspective of materials, Journal of Materials Chemistry B, 2015, 3, 7319-7333.5.     

10.     Shuo Wang, Shaoping Zhong, Chew Teck Lim (*), Hemin Nie (*), Effects of fiber alignment on stem cell–fibrous scaffold interactions, Journal of Materials Chemistry B, 2015, 3, 3358-3366.

11.     Shuo Wang, Wei Ju, Peng Shang, Lei Lei, Hemin Nie (*), Core–shell microspheres delivering FGF-2 and BMP-2 in different release patterns for bone regeneration, Journal of Materials Chemistry B, 2015, 3, 1907-1920.

12.     Dinggeng He, Shuo Wang, Lei Lei, Zengtao Hou, Peng Shang, Xiaoxiao He, Hemin Nie (*), Core–shell particles for controllable release of drug, Chemical Engineering Science, 2015, 125, 108-120.

【2007年-2012年】

1.     Hemin Nie, Yilong Fu, Chi-Hwa Wang (*), Paclitaxel and suramin-loaded core/shell microspheres in the treatment of brain tumors, Biomaterials, 2010, 31(33), 8732-8740.

2.     Hemin Nie, Shih Tak Khew, Lai Yeng Lee, Kai Ling Poh, Yen Wah Tong, Chi-Hwa Wang (*), Lysine-based peptide-functionalized PLGA foams for controlled DNA delivery, Journal of Controlled Release, 2009, 138(1), 64-70.

3.     Hemin Nie, Mei-Ling Ho, Chih-Kuang Wang, Chi-Hwa Wang, Yin-Chih Fu (*), BMP-2 plasmid loaded PLGA/HAp composite scaffolds for treatment of bone defects in nude mice, Biomaterials, 2009, 30(5), 892-901.

4.     Hemin Nie, Lai Yeng Lee, Hui Tong, Chi-Hwa Wang (*), PLGA/chitosan composites from a combination of spray drying and supercritical fluid foaming techniques: New carriers for DNA delivery, Journal of Controlled Release, 2008, 129(3), 207-214.

5.     Hemin Nie, Beng Wee Soh, Yin-Chih Fu, Chi-Hwa Wang (*), Three-dimensional fibrous PLGA/HAp composite scaffold for BMP-2 delivery, Biotechnology and Bioengineering, 2008, 99(1), 223-234.

6.     Yin-Chih Fu, Hemin Nie, Mei-Ling Ho, Chih-Kuang Wang, Chi-Hwa Wang (*), Optimized bone regeneration based on sustained release from three-dimensional fibrous PLGA/HAp composite scaffolds loaded with BMP-2, Biotechnology and Bioengineering, 2008, 99(4), 996-1006.

7.     Hemin Nie, Chi-Hwa Wang (*), Fabrication and characterization of PLGA/HAp composite scaffolds for delivery of BMP-2 plasmid DNA, Journal of Controlled Release, 2007, 120(1-2), 111-121.

奖励与荣誉

2019年甘肃省科技进步二等奖(排名第二)

项目名称:组织工程干细胞在感音神经性耳聋中的作用研究

主要完成人:钟翠萍、聂和民、马凌、张鹏志、徐学海、黄小段、安飞、蔺文魁、曲高雅、陈志峰

主要完成单位:中国人民解放军联勤保障部队第九四〇医院、湖南大学