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宋国胜

发布于:2018-02-26 星期一 14:19:17  点击数:34304

教授,博士生导师

E-mail: songgs@hnu.edu.cn; songguosheng12@sina.com



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基本信息

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宋国胜,依托化学生物传感与计量学国家重点实验室,从事纳米探针及活体成像分析的研究工作。

                 

教育背景

2014年博士毕业于东华大学;随后在苏州大学(导师:刘庄教授) 和美国斯坦福大学-医学院(分子影像中心)(导师:Jianghong Rao教授)从事博士后研究。2018年入职湖南大学。


工作履历

研究领域

生命分析化学

活体分子影像:光声成像、长余辉成像、化学发光成像、核磁成像

癌症的早期诊断、治疗及疗效检测 


科研项目

国家自然科学基金-联合基金-重点项目-项目负责人

国家自然科学基金-面上项目-项目负责人 

国家自然科学基金-青年基金-项目负责人 

国家重点研发计划纳米专项-科研骨干

湖南省重点研发计划-科技创新引领项目-子课题负责人



学术成果

代表性论文:

Z Dong, Song, G.* et al; Overcoming HypoxiaInduced Ferroptosis Resistance via 19F/1HMRI Traceable CoreShell Nanostructure. Angew. Chem. Int. Ed. 2022., https://doi.org/10.1002/ange.202206074

Guan G; Song, G.* et al; Ternary Alloy PtWMn as a Mn Nanoreservoir for High-field MRI Monitoring and Highly Selective Ferroptosis Therapy. Angew. Chem. Int. Ed. 2022. 134 (31), e202117229. (IF =15) 


Liu Y.; Song, G.*, Zhang X* et al;  Ratiometric afterglow luminescent nanoplatform enables reliable quantification and molecular imaging. Nat. Common. 2022, 13, Article number: 2216  (IF =15) 


Yang Y.; Song, G.* et al; Degradable Magnetic Nanoplatform with Hydroxide Ions Triggered Photoacoustic, MR Imaging, and Photothermal Conversion for Precise Cancer TheranosticNano Lett. 2022, 22 (8), 3228-3235 (IF =12) 


 Yue R.; Song, G.* et al; Dual key co-activated nanoplatform for switchable MRI monitoring accurate ferroptosis-based synergistic therapy, Chem, 2022, Volume 8, Issue 7, 1956-1981 (IF =25) 


Liu Y.; Song, G.*, Zhang X* et al, Chemical Design of Activatable Photoacoustic Probes for Precise Biomedical Applications, Chem. Rev. 2022, 122, 6, 6850–6918 (IF =60)


 Huang H*, Song G*, Zhou Y* et al, One-step reduction-encapsulated synthesis of Ag@ polydopamine multicore-shell nanosystem for enhanced photoacoustic imaging and photothermal-chemodynamic cancer therapy,Nano Research 2022, 15 (9), 8291-8303 (IF=10) 


Lei l, Song G*, Zhang X* et al, Metal-fluorouracil networks with disruption of mitochondrion enhanced ferroptosis for synergistic immune activation, Theranostics, 2022, (IF = 11) 


Yin B, Huan S*, Song G* et al , Tongue cancer tailored photosensitizers for NIR-II fluorescence imaging guided precise treatment, Nano Today 2022, 45, 101550 (IF=18)


Wang P, Yin X*, Song G* et al, Nanovoid-confinement and click-activated nanoreactor for synchronous delivery of prodrug pairs and precise photodynamic therapy, Nano Research, 2022, https://doi.org/10.1007/s12274-022-4615-9 (IF=10) 


Song G* et al, Recent development of a magneto-optical nanoplatform for multimodality imaging of pancreatic ductal adenocarcinoma, Nanoscale 2022, 14 (9), 3306-3323 (IF=8) 


Liao S, Liu S*, Song G* et al, A novel afterglow nanoreporter for monitoring cancer therapy, Theranostics, 2022, (IF = 11)


Teng L.; Song, G.et al; Smart Nanozyme Platform with Activity-Correlated Ratiometric Molecular Imaging for Predicating Therapeutic Effect, Angew. Chem. Int. Ed. 2021, DOI: 10.1002/anie.202110427  (IF = 15)

Suzuki Y*, Song, G.*, Fan, Q*, Ye, D* et al, Generation of hydroxyl radical-activatable ratiometric near-infrared bimodal probes for early monitoring of tumor response to therapy, Nature Communications, 2021, DOI, 10.1038/s41467-021-26380-y (IF = 15)

Lu, C. Song, G.*; Rao, J.* et al, Engineering of magnetic nanoparticles as magnetic particle imaging tracers, Chemical Society Reviews, 2021, 14 , 8102-8146 (IF = 54)

Liu H; Han L*Song, G.et al;Optical - Magnetic probe for evaluating cancer therapy, Coordination Chemistry Reviews, 2021,441, 213978 (IF = 22)

Ma Y.Song, G.* ; Zhang X.* et al. Ratiometric Semiconducting Polymer Nanoparticle for Reliable Photoacoustic Imaging of Pneumonia-Induced Vulnerable Atherosclerotic Plaque in Vivo, Nano Letters 2021, 21, 4484-4493   (IF = 12)

Shi L.; Song, G.et al; An AcidityUnlocked Nanoplatform Enables SelfBoosting ROS Generation through Upregulation of Lactate for Highly Specific Chemodynamic Therapy, Angew. Chem. Int. Ed. 2021, 60, 9562-9572   (IF = 15)

Chen, F.; Song, G.et al; Activatable Magnetic/Photoacoustic Nanoplatform for Redox-Unlocked Deep-Tissue Molecular Imaging In Vivo via Prussian Blue Nanoprobe. Analytical chemistry 2020, 92 (19), 13452-13461. (IF =6)

 Zhang, C. Song, G.*; et al, H 2 S-Activated “One-Key Triple-Lock” Bis-Metal Coordination Network for Visualizing Precise Therapy of Colon Cancer. CCS Chemistry 2020, 2126-2142.

 Lu, C. Song, G.* et al, Light-free Generation of Singlet Oxygen through Manganese-Thiophene Nanosystems for pH-Responsive Chemiluminescence Imaging and Tumor Therapy. Chem 2020, 6 (9), 2314-2334. (IF = 19)

Song, G*.; Rao, J.* et al. FeCo nanoparticles as ultrasensitive magnetic-particle-imaging tracers with photothermal and magnetothermal properties. Nature Biomedical Engineering 2020,4, 325. (IF = 18) 

Yuan, H.; Song, G* et al. Copper-Thioguanine Metallodrug with Self-reinforcing Circular Catalysis for Activatable MRI Imaging and Amplifying Specificity of Cancer Therapy, SCIENCE CHINA Chem. 2020. (IF = 6) 

 Wang, B.; Song, G* et al. Oxygen-Embedded Pentacene Based Near-Infrared Chemiluminescent Nanoprobe for Highly Selective and Sensitive Visualization of Peroxynitrite In Vivo, Anal. Chem. 2020, 92: 4154.(IF = 6) 

Wang, Y.; Song, G.* et al. Reactive Oxygen Correlated Chemiluminescent Imaging of Semiconducting Polymer Nanoplatform for Monitoring Chemodynamic Therapy. Nano Lett. 2020, 9, 6371. (IF = 12) 

Wang P.; Song G.*; Zhang X.* et al. In Vivo Monitoring Therapeutic Response by Self-Reporting Upconverting Covalent Organic Framework Nanoplatform, Chem Sci. 2020, DOI 10.1039/C9SC04875H (IF = 9.5) 

Teng, L. †Song, G. †; Zhang, X.-B.* et al. Nitric Oxide-Activated "Dual-Key-One-Lock" Nanoprobe for in Vivo Molecular Imaging and High-Specificity Cancer Therapy. J. Am. Chem. Soc. 2019, 141, 13572. (IF = 14) 

 Yin, B.; Song, G.*; et. al. Oxygen-embedded Quinoidal Acene Based Semiconducting Chromophore Nanoprobe for Amplified Photoacoustic Imaging and Photothermal Therapy. Anal. Chem. 2019, DOI: 10.1021/acs.analchem.9b04429. (IF = 6) 

Zhang, C.; Yin, X.*; Song, G.* et al. Two-Photon Supramolecular Nanoplatform for Ratiometric Bioimaging. Anal. Chem. 2019, 91, 6371. (IF = 6) 

Yin, S.; Song, G.*; Yin, X.*; Zhang, X.*, et al. Persistent Regulation of Tumor Microenvironment via Circulating Catalysis of MnFe2O4@Metal-Organic Frameworks for Enhanced Photodynamic Therapy. Adv. Funct. Mater. 2019, 29, 1901417. (IF = 15) 

Song, G.; Rao, J.* et al., A Magneto-Optical Nanoplatform for Multimodality Imaging of Tumors in Mice. ACS Nano 2019, 13, 7750. (IF = 14) 

Song, G.; Rao, J.* et al Janus Iron Oxides @ Semiconducting Polymer Nanoparticle Tracer for Cell Tracking by Magnetic Particle Imaging. Nano Lett. 2018, 18, 182. (IF = 12)

 

Before 2018

 Chen, Y.; Song, G.*; Liu, Z.*, et al. Drug-Loaded Mesoporous Tantalum Oxide Nanoparticles for Enhanced Synergetic Chemoradiotherapy with Reduced Systemic Toxicity. Small 2017, 13 (8). (IF = 10) 

Li, C.;Li, W.*; Song, G.*; Shen, J.*, et. al. Combined bortezomib-based chemotherapy and p53 gene therapy using hollow mesoporous silica nanospheres for p53 mutant non-small cell lung cancer treatment. Biomater. Sci. 2017, 5, 77. (IF = 5) 

Song, G. †; Ji, C. †; Liu, Z.* el al. TaOx decorated perfluorocarbon nanodroplets as oxygen reservoirs to overcome tumor hypoxia and enhance cancer radiotherapy. Biomaterials 2017, 112, 257. (IF = 10)

Song, G.; Liu, Z.* et al. Emerging Nanotechnology and Advanced Materials for Cancer Radiation Therapy. Adv. Mater. 2017, 29 (32). (IF = 25)

Song, G.; Hu, J.*; Liu, Z.*, et al. Degradable Molybdenum Oxide Nanosheets with Rapid Clearance and Efficient Tumor Homing Capabilities as a Therapeutic Nanoplatform. Angew. Chem. Int. Ed.2016, 55, 2122. (IF = 12) 

Song, G.; Liu, Z.* et al. Perfluorocarbon-Loaded Hollow Bi2Se3 Nanoparticles for Timely Supply of Oxygen under Near-Infrared Light to Enhance the Radiotherapy of Cancer. Adv. Mater. 2016, 28, 2716. (IF = 25) 

Song, G.; Liu, Z.* et al Catalase-Loaded TaOx Nanoshells as Bio-Nanoreactors Combining High-Z Element and Enzyme Delivery for Enhancing Radiotherapy. Adv. Mater.  2016, 28, 7143. (IF = 25)

Song, G.; Liu, Z.*, et al. All-in-One Theranostic Nanoplatform Based on Hollow TaOx for Chelator-Free Labeling Imaging, Drug Delivery, and Synergistically Enhanced Radiotherapy. Adv. Funct. Mater. 2016, 26, 8243. (IF = 15) 

Song, G.; Yang, K.*; Liu, Z.*, et al. Core-Shell MnSe@Bi2Se3 Fabricated via a Cation Exchange Method as Novel Nanotheranostics for Multimodal Imaging and Synergistic Thermoradiotherapy. Adv. Mater. 2015, 27, 6110. (IF = 25) 

Song, G.; Hu J* et al. A Low-Toxic Multifunctional Nanoplatform Based on Cu9S5@mSiO2Core-Shell Nanocomposites: Combining Photothermal- and Chemotherapies with Infrared Thermal Imaging for Cancer Treatment. Advanced Adv. Funct. Mater. 2013, 23,4281(IF = 15)

奖励与荣誉

“长江学者奖励计划”- 青年项目

湖南省“芙蓉学者”特聘教授

2021年度科睿唯安“全球高被引学者” 交叉学科

湖南省化学化工学会-青年化学奖

湖南省“湖湘青年英才”支持计划

上海市优秀博士学位论文