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王祖勇

发布于:2017-09-23 星期六 19:09:13  点击数:25631

教授,博士生导师,湖南大学“岳麓学者”晨星B岗

研究领域:生物材料与微纳制造

电子邮箱:wangzy@hnu.edu.cn

诚挚欢迎生物医学材料、化学、及机械工程相关专业背景的本科生、硕士、博士及博士后加入!

基本信息

        个人简介:男,1984年1月出生,籍贯江苏盐城,博士(工学)

        学习经历:2006年本科毕业于吉林大学生命科学院,师从房学迅教授;2009年硕士毕业于厦门大学材料学院,师从任磊教授;2013年博士毕业于新加坡国立大学机械工程系,师从生物医用材料与转化研究专家Teoh Swee Hin教授和Thian Eng San副教授、激光制造与应用专家Hong Minghui教授、干细胞与胎儿早期诊断临床医生Chan Kok Yen Jerry副教授。2014-2016年留校从事为期3年的博士后研究工作,2017年1月起全职回国工作。

        主要研究领域:主要研究聚焦生物材料微纳制造,实现材料的可控制备和生物医用功能,探索其在生命健康领域的应用,感兴趣的方向包括:软组织植介入材料 (医用补片、三维支架)、柔性健康监测器件、食品保鲜材料。

        主持国家和湖南省自然科学基金3项、湖南省科技创新平台与人才计划1项。申请中国和国际专利6项,肌腱修复支架和食品包装薄膜获国际PCT专利发表第一/通讯作者SCI/EI收录论文10余篇(Google学术:https://scholar.google.com.hk/citations?user=MmLbKs0AAAAJ&hl=zh-CN), 包括Science Advance, Advanced Healthcare Materials, Tissue Engineering等

        学生培养:诚挚欢迎校内外优秀本科生进课题组开展SIT、毕业论文等相关研究工作。实验室拟每年招收生物医学、材料、化学及机械工程相关专业研究生和博士后。

教育背景

2009.8-2013.12        博士        新加坡国立大学        (导师:Teoh Swee Hin, Hong Minghui, Thian Eng San, and Chan Kok Yen Jerry)

2006.9-2009.7          硕士        厦门大学                    (导师:任磊)

2002.9-2006.7          本科        吉林大学                    (导师:房学迅)


工作履历

2022.1-至今            教授                     湖南大学材料科学与工程学院高分子与生物材料系

2017.1-2021.12      副教授                  湖南大学材料科学与工程学院高分子与生物材料系

2014.2-2017.1        博士后研究员        新加坡国立大学生物医用材料与应用中心

2013.9-2014.2        研究员助理           新加坡国立大学光学科学与工程中心

2012.2-2012.3        访问学者              日本京都工业纤维大学


学术兼职

Materials Technology, Associate Editor

Frontiers in Bioengineering and Biotechnology, Smart Biomaterials for Precision Medicine, Co-Guest Editor

Materials Technology, Advanced Materials for Flexible Electronics, Co-Guest Editor

Journal of Physics: Materials, Bio-Responsive Materials, Co-Guest Editor

中国生物医学工程学会,高级会员

担任Elsevier、RSC、ACS和Bentham Science等集团期刊审稿人


研究领域

围绕生物材料的大尺度、可控微纳制造技术和健康应用进行探索,主要研究方向包括:

  • 软组织植介入材料 (医用补片、三维支架)

  • 柔性健康监测器件

  • 食品保鲜材料



研究概况

主持国家和湖南省自然科学基金3项、湖南省科技创新平台与人才计划1项。申请中国和国际专利6项,肌腱修复支架和食品包装薄膜获国际PCT专利发表第一/通讯作者SCI/EI收录论文10余篇(Google学术:https://scholar.google.com.hk/citations?user=MmLbKs0AAAAJ&hl=zh-CN), 包括Science Advance, Advanced Healthcare Materials, Tissue Engineering等

学术成果

A) 期刊论文 (#, 共同第一作者; *, 通讯作者)

1.        Fang Zhong, Wei Hu, Peining Zhu, Han Wang, Chao Ma, Nan Lin, Zuyong Wang*. Piezoresistive design for electronic skin: from fundamental to emerging applications. Opto-Electronic Advances. 2022 (accepted)

2.        Han Wang, Weicheng Ou, Huiyu Zhong, Jingfan He, Peixuan Wu*, Zuyong Wang*, Nian Cai, Xindu Chen, Zengxi Xue, Jianxiang Liao, Daohua Zhan, Jingsong Yao. Exploring precise deposition and influence mechanism for micro-scale serpentine structure fiber. Advances in Nano Research. 2022 (doi: 10.12989/anr.2022.12.2.000)

3.        Dan Li, Ting Guo, Fang Zhong, Wanqi Zhang, Zuyong Wang*, and Hemin Nie. Mechanically-enhanced fibre topography via electrospinning on a poly(ε-caprolactone) film for tendon tissue-engineering application. Materials Technology. 2021 (doi: 10.1080/10667857.2021.1915664)

4.        Poon Nian Lim*, Zuyong Wang, Shi Yun Tong, Bow Ho, Wilson Wang, Mamoru Aizawa, Zhijie Yang and Eng San Thian*. Silver, silicon co-substituted hydroxyapatite modulates bacteria-cell competition for enhanced osteogenic function. Biomedical Materials. 2021, 16(5): 055081

5.        Wenlong Li, Eng San Thian, Zuyong Wang*, Lei Ren*. Surface designs for antibacterial materials: from fundamentals to advanced strategies. Advanced Science. 2021, 8(19): 2100368

6.        Zuyong Wang*, Eng San Thian*, Xiang Li, Serena Best*. Bio-responsive materials for tissue regeneration. Journal of Physics: Materials. 2020, 3(2): 020201

7.        Ting Lei, Wanqi Zhang, Hu Qian, Poon Nian Lim, Eng San Thian, Pengfei Lei*, Yihe Hu*, Zuyong Wang*. Silicon-incorporated nanohydroxyapatite-reinforced poly(ε-caprolactone) film to enhance osteogenesis for bone tissue engineering applications. Colloids and Surfaces B: Biointerfaces. 2020, 187: 110714

8.        Wanqi Zhang, Zuyong Wang*, Chao Xie, Xianwei Wang, Fangfang Luo, Minghui Hong, Rui Zhou, Chao Ma, Nan Lin, Jieyu Zhang, Xuefeng Hu*, Jerry Kok Yen Chan, Feng Wen*, Yunbing Wang. Scaffold with micro/macro‐architecture for myocardial alignment engineering into complex 3D cell patterns. Advanced Healthcare Materials. 2019, 8(22): 201901015 (Inside Cover Paper)

9.        Zuyong Wang#,*, Wanqi Zhang#, Chao Xie#, Feng Wen, Chao Ma, Nan Lin, Eng San Thian, Xianwei Wang*. Geometric anisotropy on biomaterials surface for vascular scaffold design: engineering and biological advances. Journal of Physics: Materials. 2019, 2(3): 032003

10.     Zuyong Wang*, Won Jae Lee, Bryan Thean Howe Koh, Minghui Hong, Wilson Wang, Poon Nian Lim, Jason Feng, Lisa Soyeon Park, Michael Kim, Eng San Thian*. Functional regeneration of tendons using scaffolds with physical anisotropy engineered via microarchitectural manipulation. Science Advances. 2018, 4: eaat4537

11.     Dong Wang, Chris Steffi, Zuyong Wang, Chee Hoe Kong, Poon Nian Lim, Zhilong Shi, Eng San Thian, Wilson Wang. Beta-cyclodextrin modified mesoporous bioactive glass nanoparticles/silk fibroin hybrid nanofibers as an implantable estradiol delivery system for the potential treatment of osteoporosis. Nanoscale. 2018, 10 (38): 18341-18353

12.     Chris Steffi, Dong Wang, Chee Hoe Kong, Zuyong Wang, Poon Nian Lim, Zhilong Shi, Eng San Thian, Wilson Wang. Estradiol-loaded poly(ε-caprolactone)/silk fibroin electrospun microfibers decrease osteoclast activity and retain osteoblast function. ACS Applied Materials & Interfaces. 2018, 10(12): 9988–9998

13.     Zuyong Wang*, Rui Zhou, Feng Wen, Rongkai Zhang, Lei Ren, Swee Hin Teoh, Minghui Hong*. Reliable laser fabrication: the quest for responsive biomaterials surface. Journal of Materials Chemistry B. 2018, 6(22): 3612-3631

14.     Poon Nian Lim, Toshiisa Konishi, Zuyong Wang, Jason Feng, Jing Han, Zhijie Yang, Eng San Thian. Enhancing osteoconductivity and biocompatibility of silver-substituted apatite in-vivo through silicon co-substitution. Materials Letters. 2018, 212(00): 90-93

15.     Kaichen Xu#, Zuyong Wang#, Chuan Fu Tan, Ning Kang, Lianwei Chen, Lei Ren, Eng San Thian, Ghim Wei Ho, Rong Ji, Minghui Hong. Uniaxially stretched flexible surface plasmon resonance film for versatile surface enhanced raman scattering diagnostics. ACS Applied Materials & Interfaces. 2017, 9(31): 26341-26349

16.     Zuyong Wang, Feng Wen, Rongkai Zhang, Qinyuan Zhang. Modulated nitric oxide delivery in three-dimensional biomaterials for vascular functionality. MRS Communications. 2017, 7(3): 348-360 (Invited Paper)

17.     Poon Nian Lim, Zuyong Wang, Dong Wang, Toshiisa Konishi, Eng San Thian. Development in additive printing for musculoskeletal tissue engineering-bone and tendon. Current Opinion in Biomedical Engineering. 2017, 2: 99-104 (New Journal, Invited Paper)

18.     Zuyong Wang, Feng Wen, Poon Nian Lim, Qinyuan Zhang, Toshiisa Konishi, Dong Wang, Swee Hin Teoh, Eng San Thian. Nanomaterial scaffolds to regenerate musculoskeletal tissue: signals from within for neovessel formation. Drug Discovery Today. 2017, 22(9): 1385-1391 (Invited Paper)

19.     Poon Nian Lim, Jason Feng, Zuyong Wang, Mark Chong, Toshiisa Konishi, Lay Geok Tan, Jerry Chan, Eng San Thian. In-vivo evaluation of subcutaneously implanted cell-Loaded apatite microcarriers for osteogenic potency. Journal of Materials Science: Materials in Medicine. 2017, 28(6): 86

20.     Shi Yun Tong#, Zuyong Wang#,*, Poon Nian Lim, Wilson Wang, Eng San Thian*. Uniformly-dispersed nanohydroxapatite-reinforced poly(epsilon-caprolactone) composite films for tendon tissue engineering application. Materials Science and Engineering C: Materials for Biological Applications. 2017, 70(Pt 2): 1149-1155 (Invited Paper)

21.     Poon Nian Lim, Zuyong Wang, Lei Chang, Toshiisa Konishi, Cleo Choong, Bow Ho, Eng San Thian. A multi-material coating containing chemically-modified apatites for combined enhanced bioactivity and reduced infection via a drop-on-demand micro-dispensing technique. Journal of Materials Science: Materials in Medicine. 2017, 28(1): 3

22.     Yang Wu#, Zuyong Wang#, Ying Hsi Jerry Fuh, San Yoke Wong, Wilson Wang, Eng San Thian. Direct E-jet printing of three-dimensional fibrous scaffold for tendon tissue engineering. Journal of Biomedical Materials Research Part B: Applied Biomaterials. 2017, 105(3): 616–627

23.     Yang Wu, Zuyong Wang, Jerry Ying His Fuh, Yoke San Wong, Wilson Wang, Eng San Thian. Mechanically-enhanced three-dimensional scaffold with anisotropic morphology for tendon regeneration. Journal of Materials Science: Materials in Medicine. 2016, 27(7): 115 (Covered Paper)

24.     Zuyong Wang, Zheren Du, Jerry Kok Yen Chan, Swee Hin Teoh, Eng San Thian, Minghui Hong. Direct laser microperforation of bioresponsive surface-patterned films with through-hole arrays for vascular tissue-tngineering application. ACS Biomaterials-Science & Engineering. 2015, 1(12): 1239-1249

25.     Zuyong Wang, Swee Hin Teoh, Minghui Hong, Fangfang Luo, Yiling Erin Teo, Jerry Kok Yen Chan, Eng San Thian. Dual-mcrostructured porous, anisotropic film for biomimicking of endothelial basement membrane. ACS Applied Materials & Interfaces. 2015, 7(24): 13445-13456

26.     Qinyuan Zhang, Zuyong Wang, Feng Wen, Lei Ren, Jun Li, Swee Hin Teoh, Eng San Thian. Gelatin-siloxane nanoparticles to deliver nitric oxide for vascular cell regulation: synthesis, cytocompatibility, and cellular responses. Journal of Biomedical Materials Research Part A. 2015, 103(3): 929-938

27.     Youyong Yuan, Zuyong Wang, Pingqiang Cai, Jie Liu, Lun-De Liao, Minghui Hong, Xiaodong Chen, Nitish Thakor, Bin Liu. Conjugated polymer and drug co-encapsulated nanoparticles for chemo- and photo-thermal combination therapy with two-photon regulated fast drug release. Nanoscale. 2015, 7: 3067-3076

28.     Zuyong Wang, Swee Hin Teoh, Nuryanti Binti Johana, Mark Seow Khoon Chong, Erin Yiling Teo, Minghui Hong, Jerry Kok Yen Chan, Eng San Thian. Enhancing mesenchymal stem cell response using uniaxially stretched poly(epsilon-caprolactone) film micropatterns for vascular tissue engineering application. Journal of Materials Chemistry B. 2014, 2: 5898-5909.

29.     Zuyong Wang, Jing Lim, Yeow Siong Ho, Qinyuan Zhang, Mark Seow Khoon Chong, Min Tang, Minhui Hong, Jerry Kok Yen Chan, Swee Hin Teoh, Eng San Thian. Biomimetic three-dimensional anisotropic geometries by uniaxial stretching of poly(epsilon-caprolactone) films: degradation and mesenchymal stem cell responses. Journal of Biomedical Materials Research Part A. 2014, 102A: 2197-2207

30.     Zuyong Wang, Erin Yiling Teo, Mark Seow Khoon Chong, Qinyuan Zhang, Jing Lim, Zhiyong Zhang, Minghui Hong, Eng San Thian, Jerry Kok Yen Chan, Swee Hin Teoh. Biomimetic three-dimensional anisotropic geometries by uniaxial stretch of poly(epsilon-caprolactone) films for mesenchymal stem cell proliferation, alignment, and myogenic differentiation. Tissue Engineering Part C: Methods. 2013, 19(7): 538-549 (Featured Press, Immediate Release News)

 

B) 专利

1.        王祖勇, 张皓哲, 吝楠, 马超. 一种TBJ组织修复薄膜型支架及其制备方法. 202011146218X (授权)

2.        王祖勇, 章万奇, 吝楠, 马超. 一种采用离子和几何图案信号协同构建医用骨膜支架的方法. 201910898657.7 (授权)

3.        Eng San Thian, Zuyong Wang, Yi Min Tan, Bow Ho. A Packaging Material and Method of Preparation Thereof. 10201610373X (Filed in SG on 9 December 2016); WO 2018/106191 (Filled in WIPO|PCT on 07 December 2017, International publication on 14 June 2018)

4.        Eng San Thian, Zuyong Wang, Wilson Wang, Minghui Hong. Tissue Scaffold Device and Method for Fabricating Thereof. 10201407543V (Filled in SG on 13 November 2014); WO 2016/076791 A1 (Filling in WIPO|PCT on 3 November 2015, International publication on 19 May 2016); 15/526,429 (Filed in US on 12 May 2017); 11201703922T (Filed in SG on 12 May 2017); 15859055.4 (Filed in EU on 19 May 2017); 201580073288.8 (Filed in CN on 13 July 2017, 授权日期2020/09/08 CN107206121B)

 

 


奖励与荣誉