header
蔡仁

发布于:2020-05-08 星期五 15:19:18  点击数:17989

教授、博士生导师 湖南大学“岳麓学者” 

研究领域:分析化学、纳米医学、生物传感器

电子邮件:cairen@hnu.edu.cn

欢迎有志的本科生、硕士生、博士生和博士后加盟。


基本信息

蔡仁男,毕业于美国佛罗里达大学,获分析化学博士学位,师从谭蔚泓教授。现任湖南大学材料科学与工程学院教授,博士生导师。目前,主要从事新型分析检测技术、化学生物学与肿瘤诊疗生物传感器等研究。至今发表SCI学术论文50篇,其中包括在J. Am. Chem. Soc.,Anal. Chem. 国际顶级学术期刊发表第一作者或通讯作者论文32篇,相关研究成果被C&EN等知名媒体所报道。获得湖南省自然科学基金优秀青年基金资助。另外,兼任Journal of Leather Science and Engineering 杂志青年编委。

联系方式:cairen@hnu.edu.cn


教育背景

2013—2017  佛罗里达大学 (美国)  化学系 博士


工作履历

2019.4— 2019.10  访问研究员,  佛罗里达大学 (美国)  化学系         

2019.1— 2019.3   博士后研究员,西北太平洋国家实验室 (美国)  材料科学研究室         

2018.10— 2019.1 访问研究员,   基础科学研究所 (韩国 蔚山)  软体和活性材料研究中心 

2018.1— 2018.12 博士后研究员,佛罗里达大学 (美国)  化学系         

2011.8—2013.8    研究助理,      南洋理工大学 (新加坡)  材料科学与工程学院       


学术兼职

兼任Journal of Leather Science and Engineering 杂志青年编委;Energies 杂志(IF 3.0)专题编辑(Topic Editor).

研究领域

新型分析检测技术

生物材料及肿瘤治疗

生物传感器


学术成果

Publications

54. Zuocai Zhang, Tianyun Lu, Dan Yang, Shaorong Lu,* Ren Cai,*  Weihong Tan. A Dual-function Sensor for Highly Sensitive Detection of Flame and Humidity. Small 2022, DOI:10.1002/smll.202203334.

53. Jingxian Li,  Mengyu Luo, Hongfen Yang,  Chao Ma,  Ren Cai,*  Weihong Tan. Novel Dual-Signal Electrochemiluminescence Aptasensor Involving the Resonance Energy Transform System for Kanamycin Detection. Anal. Chem. 2022, 94, 16, 6410–6416.

52. Jia Ge, Demiao Ma, Guohang Duan, Zhongyue Yan, Like Yang, Dan Yang,  Ren Cai,*  Weihong Tan. A novel probe for tetracyclines detection and its applications in cell imaging based on fluorescent WS2 quantum dots.  Analytica Chimica Acta 2022, 1221, 340130.

51. Chengyi Hong, Jingjing Wang,  Yuying  Wang,  Zhiyong Huang,  Hongfen Yang,*  Dan Yang, Ren Cai,*  Weihong Tan. Fluorescence detection of milk allergen β-lactoglobulin based on aptamer and WSnanosheets. J. Mater. Chem. B 2022, https://doi.org/10.1039/D2TB00263A

50. Jingxian Li, Mengyu Luo, Can Jin, Penghui Zhang, Hongfen Yang,* Ren Cai,* Weihong Tan. Plasmon-Enhanced Electrochemiluminescence of PTP Decorated Eu-MOF-Based Pt-Tipped Au Bimetallic Nanorods for Lincomycin Assay. ACS Appl. Mater. Interfaces. 2022, 14, 1, 383–389

49. Hao Fu, Dan Yang, Di Qiu, Chun-Hua Yan, Ren Cai,* Yaping Du,* Weihong Tan. Highly Stable 3D Supercuboids to 2D ZnSe Nanosheets: Forming for A High-Efficient Catalysis System. J. Phys. Chem. Lett. 2022, 13, 1855–1862. 

48. Zuocai Zhang, Tianyun Lu, Dan Yang,* Shaorong Lu,* Ren Cai,* and Weihong Tan. A high-wet-strength biofilm for readable and highly sensitive humidity sensors. Nano Lett. 2021, 21, 21, 9030–9037.

47. Kuo Liu, Dan Yang,* Hongfen Yang,* Shaorong Lu,* Ren Cai,* and Weihong Tan. Multifunctional shape memory films for a flexible electrical sensor, Macromol. Mater. Eng. 2021, 306, 12, 2100580.

46. Ren Cai, Huandong Xiang, Dan Yang, Keng-Te Lin, Yuanzheng Wu, Ruyi Zhou, Zhanjun Gu, Liang Yan,* Yuliang Zhao,* Weihong Tan.* Plasmonic AuPt@CuS heterostructure with enhanced synergistic efficacy for radiophotothermal therapy. J. Am. Chem. Soc. 2021,143, 39, 16113–16127.

45. Chengyi Hong, Lingling Chen, Chenyue Wu, Dan Yang, Jia-Yong Dai, Zhiyong Huang,  Ren Cai,* and Weihong Tan. Green synthesis of Au@WSe2 hybrid nanostructures with the enhanced peroxidase-like activity for sensitive colorimetric detection of glucose. Nano Research 2022, 15, 1587–1592.

44. Yongchun Liu, Xinhao Li, Yu Shi, Youjuan Wang, Xiaojing Zhao, Xiangyang Gong, Ren Cai, Guosheng Song, Mei Chen,* Xiaobing Zhang. Two-dimensional intermetallic PtBi/Pt core/shell nanoplates overcome tumor hypoxia for enhanced cancer therapy. Nanoscale, 2021,13, 14245-14253.

43. Zuocai Zhang, Dan Yang, Shaorong Lu,* Ren Cai,* and Weihong Tan, Rapid Water-responsive Shape Memory Films for Smart Resistive Bending Sensors, Nano Today 2021, 38, 101202.

42. Chengyi Hong, Xiaoxia Zhang, Sishi Ye, Hongfen Yang,* Zhiyong Huang,* Dan Yang,* Ren Cai,* and Weihong Tan, Aptamer-Pendant DNA Tetrahedron Nanostructure Probe for Ultrasensitive Detection of Tetracycline by Coupling Target-Triggered Rolling Circle Amplification.  ACS Appl. Mater. Interfaces 2021, 13, 17, 19695–19700.

41. Zuocai Zhang, Dan Yang, Hongfen Yang, Yuqi Li, Shaorong Lu,* Ren Cai,* and Weihong Tan. A hydrophobic sisal cellulose microcrystal film for fire alarm sensors. Nano Lett. 202121, 5, 2104–2110.

40. Jia Ge, Jian-Hua Yu, Hongfen Yang,* Dan Yang* and Ren Cai,* Human serum albumin templated MnO2 nanosheets as an efficient biomimetic oxidase for biomolecule sensing. J. Mater. Chem. B 2020, 8, 11090-11095.

39. Chengyi Hong, Xiaoxia Zhang, Chenyue Wu, Qin Chen, Hongfen Yang*, Dan Yang*, Zhiyong Huang, Ren Cai,* and Weihong Tan*, On-Site Colorimetric Detection of Cholesterol Based on Polypyrrole Nanoparticles. ACS Appl. Mater. Interfaces 2020, 12 (49), 54426-54432.

38. Jia Ge, Yun Hu, Ruijie Deng, Zhaohui Li, Kaixiang Zhang, Muling Shi, Dan Yang,* Ren Cai,* and Weihong Tan.* Highly sensitive microRNA detection by coupling nicking-enhanced rolling circle amplification with MoS2 quantum dots. Anal. Chem. 2020, 92, 19, 13588–13594.

37. Xigao Chen, Liping Qiu, Ren Cai, Cheng Cui, Long Li, Jian-Hui Jiang, Weihong Tan. Aptamer-Directed Protein-Specific Multiple Modifications of Membrane Glycoproteins on Living Cells. ACS Appl. Mater. Interfaces 2020, 12, 34, 37845–37850.

36. Yu Yang, Wenjun Zhu, Liang Cheng, Ren Cai, Xuan Yi, Jiaxuan He, Xiaoshu Pan, Lu Yang, Kai Yang, Zhuang Liu, Weihong Tan, Meiwan Chen. Tumor microenvironment (TME)-activatable circular aptamer-PEG as an effective hierarchical-targeting molecular medicine for photodynamic therapy. Biomaterials 2020, 119971.

35. Ren Cai, Haiyan Jin, Dan Yang, Keng-Te Lin, Jianke Sun, Zhuo Chen, Xiaobing Zhang, and Weihong Tan.* Generalized Preparation of Au NP@Ni(OH)2 Yolk-Shell Nanoparticles and Their Superior Catalytical Activity for Oxygen Evolution Reaction. Nano Energy 2020, 104542.

34. Ren Cai, Dan Yang, Xigao Chen, Yifan Lyv, He Zhen, Kangfu Chen, Yu Yang, Liqin Zhang, Jia Ge, Lian Xia, Yuliang Zhao, Weihong Tan.* 3D Halos Assembled from Fe3O4/Au NPs with Enhanced Catalytic and Optical Properties. Nanoscale 2019,11 (43), 20968-20976.

33. Ren Cai, Yaping Du, Dan Yang, Guohua Jia, Bowen Zhu, Yifan Lyu, Liping Qiu, Xigao Chen, Dechao Chen, Wei Chen, Liqin Zhang, Meng Luo,Lu Yang, Yuliang Zhao, Weihong Tan.* Free-standing 2D nanorafts by assembly of 1D nanorods for biomolecule sensing. Nanoscale 2019,11, 12169-12176.

32. Ren Cai, Dan Yang, Yifan Lyu, Bowen Zhu, Zhen He, Yusuke Kitamura, Liping Qiu, Xigao Chen, Yuliang Zhao, Zhuo Chen,* Weihong Tan.* Generalized preparation of 2D quasi-nanosheets via self-assembly of nanoparticles. J. Am. Chem. Soc. 2019, 141, 1725-1734.

31. Ren Cai, Dan Yang, Liang Yan, Feng Tian, Jichao Zhang, Yifan Lyv, Kangfu Chen, Chengyi Hong, Xigao Chen, Yuliang Zhao, Zhuo Chen, Weihong Tan.* Free-floating 2D Nanosheets With Superlattice Assembled From Fe3O4 Nanoparticles. ACS Appl. Nano Mater. 2018, 1 (10), 5389-5395.

30. Ren Cai, D. Yang, X. Chen, Y. Huang, Y. Lyv, J. He, M. Shi, I-T. Teng, S. Wan, W. Hou, Weihong Tan.* Three Dimensional Multipod Superstructure based on Cu(OH)2 as a Highly Efficient Nanozyme. J. Mater. Chem. B 2016, 4, 4657-4661.

29. Ren Cai, D. Yang, S. Peng, X. Chen, Y. Huang, Y. Liu, W. Hou, S. Yang, Z. Liu, and Weihong Tan.* Single Nanoparticle to 3D Supercage: Framing for an Artificial Enzyme System. J. Am. Chem. Soc. 2015, 137, 13957-13963. (C&EN NEWS, http://cen.acs.org/articles/93/web/2015/10/Tiny-Boxes-Hold-Catalytic-Surprise.html).

28. Ren Cai, D. Yang, L. Zhang, J. Wu, X. Chen, Z. Zhang, H. Huo, Q. Yan, Weihong Tan,* Fabrication of ultrathin Zn(OH)2 nanosheets as drug carriers. Nano Research 2016, 9, 2520–2530.

27. Ren Cai, D. Yang, L. Zhang, L. Qiu, H. Liang, X. Chen, Z. Zhang, S. Cansiz, S. Wan, Q. Yan, Weihong Tan,* A facile process for the preparation of three-dimensional (3D) hollow Zn(OH)2 nanoflowers at room temperature. Chem. Eur. J. 2016, 22(32): 11143-11147 (Hot Paper, Spotlight by Angew. Chem. Int. Ed. DOI: 10.1002/anie201683213).

26. Ren Cai, Y. Du, S. Peng, H. Bi, W. Zhang, D. Yang, J. Chen, T. M. Lim, H. Zhang, Q. Yan, The Synthesis of Porous Metal MCO3 (M=Mn, Co, Ca) Hollow Microstructures and Adsorption Property Thereof. Chem. Eur. J. 2014, 20(2): 421-425.

25. Ren Cai, J. Chen, D. Yang, Z. Zeng, S. Peng, J. Wu, W. Zhang, C. Zhu, T. -M. Lim, H. Zhang, Q. Yan, Solvothermal-induced Conversion of One-Dimensional Multi-layer Nanotubes to Two-Dimensional Hydrophilic VOx Nanosheets: Synthesis and Water Treatment Application. ACS Appl. Mater. Interfaces 2013, 5(20): 10389-10394.

24. Ren Cai, Y. Du, W. Zhang, H. Tan, T. Zeng, X. Huang, H. Yang, C. Chen, H. Liu, J. Zhu, S. Peng, J. Chen, Y. Zhao, H. Wu, Y. Huang, R. Xu, T. -M. Lim, Q. Zhang, H. Zhang, Q. Yan, Synthesis of Porous Amorphous FePO4 Nanotubes and Their Li Storage Properties. Chem. Eur. J. 2013, 19(5): 1568-1572.

23. Ren Cai, H. Li, W. Zhang, H. Tan, D. Yang, H. H. Hng, T. M. Lim, Q. Yan, Controlled Synthesis of Double-wall a-FePO4 Nanotubes and Their LIB Cathode Properties. Small, 2013, 9(7): 1036-1041.

22. Ren Cai, J. Chen, J. Zhu, C. Xu, W. Zhang, C. Zhang, W. Shi, H. Tan, D. Yang, H. H. Hng, T. M. Lim, Q. Yan, Synthesis of CuxS/Cu Nanotubes and Their Lithium Storage Properties. J. Phys. Chem. C 2012, 116 (23), 12468-12474.

21. Ren Cai, B. Deng, H. JiangY. YuM. YuL. LiJ. Li. Radiation Induced Graft Polymerization of a Fluorinated Acrylate onto Fabric. Rad. Phys. Chem. 2012, 81 (9), 1354-1356.

20. B. Deng , Ren Cai, Y. Yu, H. Jiang, C. Wang, J. Li, L. Li, M. Yu, J. Li, L. Xie, Q. Huang, C. Fan. Laundering Durability of Superhydro-phobic Cotton Fabric. Adv. Mater. 2010, 22 (48), 5473-5477. 

19. J. Ge#, Ren Cai#, L. Yang, L. Zhang, Y. Jiang, Y. Yang, C. Cui, S. Wan, X. Chu, Weihong Tan.* Core-Shell HA-Au NPs@Si NPs Nanoprobe for Sensitive Fluorescence Hyaluronidase Detection and Cell Imaging. ACS Sustain. Chem. Eng. 2018, 6 (12), 16555-16562. 

18. J. Ge, Ren Cai, X. Chen, Q. Wu, L. Zhang, Y. Jiang, C. Cui, S. Wan, W. Tan. Facile approach to prepare HSA-templated MnO2 nanosheets as oxidase mimic for colorimetric detection of glutathione. Talanta 2019, 195, 40-45.

17. Yifan Lyu, Yian Guo, Ren Cai, Ruizi Peng, Chengyi Hong, Xigao Chen, Weijia Hou, Xiaowei Li, Jie Tan, Yuxiu Zou, Xiaobing Zhang, Qiaoling Liu, Weihong Tan. Spherically Directed Synthesis and Enhanced Cellular Internalization of Metal-Crosslinked DNA Micelles. Chem 2019, 5 (4), 913-928.

16. L. Yang, H. Sun, Y. Liu, W. Hou, Y. Yang, Ren Cai, C. Cui, P. Zhang, X. Pan, X. Li, L. Li, B. S Sumerlin, Weihong Tan. SelfAssembled AptamerGrafted Hyperbranched Polymer Nanocarrier for Targeted and Photoresponsive Drug Delivery. Angew. Chem. Int. Ed. 2018, 57 (52), 17048-17052.

15. X. Li, C A. Figg, R. Wang, Y. Jiang, Y. Lyu, H. Sun, Y. Liu, Y. Wang, I-T. Teng, W. Hou, Ren Cai, C. Cui, L. Li, X. Pan, B. S Sumerlin, W. Tan. CrossLinked Aptamer–Lipid Micelles for Excellent Stability and Specificity in TargetCell Recognition. Angew. Chem. Int. Ed. 2018,130 (36), 11763-11767.

14. Y. Lyu, I-T. Teng, L. Zhang, Y. Guo, Ren Cai, X. Zhang, L. Qiu, W. Tan. A comprehensive regression model for dissociation equilibria of cell-specific aptamers. Anal. Chem. 2018, 90, 10487-10493.

13. Lyu, Y.; Wu, C.; Heinke, C.; Han, D.; Cai, Ren; Teng, I. T.; Liu, Y.; Liu, H.; Zhang, X.; Liu, Q.; Tan, W., Constructing Smart Protocells with Built-In DNA Computational Core to Eliminate Exogenous Challenge. J. Am. Chem. Soc. 2018, 140 (22), 6912-6920.  

12. Y. Huang, H. C. Pappas, L. Zhang, S. Wang, Ren Cai, W. Tan, S. Wang, D. G. Whitten, and K. S. Schanze, Selective Imaging and Inactivation of Bacteria over Mammalian Cells by Imidazolium Substituted Polythiophene, Chem. Mater. 2017, 29 (15), 6389–6395.

11. S. Wang, L. Zhang, S. Wan, S. Cansiz, C. Cui, Y. Liu, Ren Cai, C. Hong, I-T. Teng, M. Shi, Y. Wu, Y. Dong, and W. Tan, Apta-sensor with Expanded Nucleotide Using DNA Nanotetrahedra for Electrochemical Detection of Cancerous Exosomes, ACS Nano 2017, 11 (4), 3943–3949. 

10. Y. Wang, C. Wu, T. Chen, H. Sun, S. Cansiz, L. Zhang, C. Cui, W. Hou, Y. Wu, S. Wan, Ren Cai, Y. Liu, B. Sumerlin, X. Zhang, W. Tan, DNA micelle flares: a study of the basic properties that contribute to enhanced stability and binding affinity in complex biological systems, Chem. Sci. 2016, 7, 6041-6049.

9.  X. Zhang, J. Ge, Y. Xue, B. Lei, D. Yan, N. Li, Z. Liu, Y. Du, Ren Cai, Controlled Synthesis of Ultrathin Lanthanide Oxide Nanosheets and Their Promising pH-Controlled Anticancer Drug Delivery. Chem. Eur. J. 2015, 21 (34), 12204-12204. (Back Cover)

8. S. Cansiz, L. Zhang, C. Wu, Y. Wu, I. T. Teng, W. Hou, Y. Wang, S. Wan,Ren Cai, C. Jin, Q. Liu, W. Tan, DNA Aptamer Based Nanodrugs: Molecular Engineering for Efficiency. Chem. Asian J. 2015, 24 (15), 2155-2162.

7. S. Peng, L. Li, H. Tan, Ren Cai, W. Shi, C. Li, S. Ramakrishna, M. Srinivasan, S. G. Mhaisalkar, Q. Yan, MS2 (M= Co and Ni) Hollow Spheres with Tunable Interiors for High-performance Supercapacitors and Photovoltaics. Adv. Funct. Mater. 2014, 24 (15), 2155-2162.

6. X. Zhou, G. Wu, J. Wu, H. Yang, J. Wang, G. Gao, Ren Cai, Q. Yan, Multiwall carbon nanotubes-V2O5 integrated composite with nanosized architecture as cathode material for high performance lithium ion batteries. J. Mater. Chem. A 2013, 1, 15459-15468.

5. S. Peng, L. Li, C. Li, H. Tan, Ren Cai, H. Yu, S. Mhaisalkar, M. Srinivasan, S. Ramakrishna, Q. Yan, In situ growth of NiCo2S4 nanosheets on graphene for high-performance supercapacitors. Chem. Commun. 2013, 49, 10178-10180.

4. X. Huang, J. Chen, H. Yu, Ren Cai, S. Peng, H. H. Hng, Q. Yan, Carbon buffered-transition metal oxide nanoparticle-graphene hybrid nanosheets as high-performance anode materials for lithium ion batteries. J. Mater. Chem. A 2013, 1,6901-6907.

3. S. Peng, L. Li, H. Tan, Y. Wu, Ren Cai, X. Huang, P. Zhu, S. Ramakrishna, M. Srinivasan, S. G. Mhaisalkar, Q. Yan, Monodispersed Ag nanoparticles loaded on the PVP-assisted synthetic Bi2O2CO3 microspheres with enhanced photocatalytic and supercapacitive performances. J. Mater. Chem. A 2013, 1, 7630-7638.

2. D. Yang, J. Zhu, X. Rui, H. Tan, Ren Cai, H. E. Hoster, D. Y. W. Yu, H. H. Hng, Q. Yan, Synthesis of Cobalt Phosphides and Their Application as Anodes for Lithium Ion Batteries. ACS Appl. Mater. Interfaces 2013, 5(3): 1093-1099.

1. X. Huang, J. Chen, H. Yu, S. Peng, Ren Cai, Q. Yan, H. H. Hng, Immobilization of plant polyphenol stabilized-Sn nanoparticles onto carbon nanotubes and their application in rechargeable lithium ion batteries. RSC Adv. 2013, 3(16): 5310-5313.


奖励与荣誉

湖南省自然科学基金优秀青年基金