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程立杰

发布于:2021-08-11 星期三 20:01:53  点击数:7947

教授博士生导师

E-mail: ljcheng@hnu.edu.cn

基本信息

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程立杰,湖南大学化学化工学院教授博士生导师岳麓学者。2013年博士毕业于南开大学元素有机化学国家重点实验室,师从中国科学院院士周其林教授。之后分别在英国帝国理工学院以及美国伊利诺伊大学芝加哥分校进行了博士后研究。主要研究方向为金属有机化学、协同催化、不对称催化、天然产物及手性药物分子合成等。迄今在国际著名期刊上发表论文17篇,其中以第一作者(含共一)身份发表论文14篇,包括J. Am. Chem. Soc.(4篇)、Angew. Chem. Int. Ed.(3篇)、Chem. Sci.(2篇)、Chem. Soc. Rev.(1篇)、Acc. Chem. Res.(1篇)等。研究成果多次被SynfactsOrganic Chemistry Portal等作为亮点评述或专题报道。


课题组现招聘副教授(编制内)、讲师(编制内)、博士后和科研助理多名,待遇从优,欢迎邮件咨询。欢迎报考博士(可以科研助理身份提前入组)、硕士研究生。随时欢迎联合培养学生和对有机化学感兴趣的本科生加入。

教育背景

2008.09-2013.07 南开大学  理学博士(有机化学) 导师:周其林院士

2004.09-2008.07 河北大学  理学学士(材料化学)

工作履历

2021-至今    湖南大学化学化工学院,教授博士生导师

2016-2021    伊利诺伊大学芝加哥分校(UIC) 博士后 

2013-2016    帝国理工学院  博士后

学术兼职

研究领域

金属有机化学、协同催化、不对称催化、天然产物及手性药物分子合成等

学术成果

发表主要论文:

1.     Cheng, L.-J.*; Mankad, N. P.* Copper-Catalyzed Carbonylative Coupling of Alkyl Halides. Acc. Chem. Res. 202154, 2261-2274. 

2.     Cheng, L.-J.; Zhao, S.; Mankad, N. P.* One-Step Synthesis of Acylboron Compounds via Cu-Catalyzed Carbonylative Borylation of Alkyl Halides. Angew. Chem. Int. Ed. 202160, 2094-2098.

3.     Cheng, L.-J.; Mankad, N. P.* C-C and C-X Coupling Reactions of Unactivated Alkyl Electrophiles Using Copper Catalysis. Chem. Soc. Rev. 202049, 8036-8064.

4.     Cheng, L.-J.; Mankad, N. P.* Cu-Catalyzed Carbonylative Silylation of Alkyl Halides: Efficient Access to Acylsilanes. J. Am. Chem. Soc. 2020142, 80-84.

5.     Cheng, L.-J.; Mankad, N. P.* Heterobimetallic Control of Regioselectivity in Alkyne Hydrostannylation: Divergent Syntheses of α- and (E)-β-Vinylstannanes via Cooperative Sn-H Bond Activation. J. Am. Chem. Soc. 2019141, 3710-3716.

6.     Cheng, L.-J.; Mankad, N. P.* Cu-Catalyzed Borocarbonylative Coupling of Internal Alkynes with Unactivated Alkyl Halides: Modular Synthesis of Tetrasubstituted β-Borylenones, Angew. Chem. Int. Ed20185710328-10332.

7.     Cheng, L.-J.; Islam, S. M.; Mankad, N. P.* Synthesis of Allylic Alcohols via Cu-Catalyzed Hydrocarbonylative Coupling of Alkynes with Alkyl Halides, J. Am. Chem. Soc2018140, 1159-1164.

8.     Cheng, L.-J.; Mankad, N. P.* Cu-Catalyzed Hydrocarbonylative C–C Coupling of Terminal Alkynes with Alkyl Iodides, J. Am. Chem. Soc2017139, 10200-10203. 

9.     Cheng, L.-J.; Cordier, C. J.* Catalytic Nucleophilic Fluorination of Secondary and Tertiary Propargylic Electrophiles with a Copper–N-Heterocyclic Carbene Complex, Angew. Chem. Int. Ed201554, 13734-13738.

10.  Cheng, L.-J.; Brown, A. P. N.; Cordier, C. J.* Enantioselective Propargylic [1,3]-Rearrangements: Copper-catalyzed O-to-N Migrations toward C–N Bond Formation, Chem. Sci. 20178, 4299-4305.

11.  Liu, Y.#Cheng, L.-J. #; Yue, H.-T.; Che, W.; Xie, J.-H.*; Zhou, Q.-L. Divergent Enantioselective Synthesis of Hapalindole-Type Alkaloids Using Catalytic Asymmetric Hydrogenation of a Ketone to Construct the Chiral Core Structure,
Chem. Sci.2016, 7, 4725-4729 (#co-first author).

12.  Cheng, L.-J.; Xie, J.-H.*; Chen, Y.; Wang, L.-X.; Zhou, Q.-L.* Enantioselective Total Synthesis of (−)-Δ8-THC and (−)-Δ9-THC via Catalytic Asymmetric Hydrogenation and SNAr Cyclization, Org. Lett. 201315, 764-767.

13.  Cheng, L.-J.; Xie, J.-H.*; Wang, L.-X.; Zhou, Q.-L.* Enantioselective Synthesis of (−)-CP-55940 via Ruthenium-Catalyzed Asymmetric Hydrogenation of Ketone, Adv. Synth. Catal. 2012354, 1105-1113. 

14. Cheng, L.-J.; Brown, A. P. N.; Cordier, C. J.* From Propargylic Fluorinations to [1,3]-Rearrangements: Anion and Ligand Effects in Cu-Acetylide Chemistry. Synlett. 2018, 29, 1675-1682.