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吕一帆

发布于:2020-09-16 星期三 10:52:49 点击数:4546

副教授,硕士生导师

Email: lvyifan1990@hnu.edu.cn; lvyifan1990@hotmail.com

基本信息

吕一帆,分析化学博士,副教授,岳麓学者,硕士生导师。长期从事DNA纳米技术相关的应用研究,并取得了一系列原创性的研究成果。以第一作者或共同第一作者在Nature Nanotechnology,Chem (Cell Press),Journal of the American Chemical Society,Nature Protocols,Chemical Science,Trends in Biochemical Sciences等国际著名期刊发表论文11篇。


教育背景

2015.09-2017.09     佛罗里达大学                   分析化学专业      联合培养博士                 导师:谭蔚泓教授

2012.09-2017.12     湖南大学化学化工学院     分析化学专业      研究生/博士(直博)      导师:谭蔚泓教授

2008.09-2012.06     湖南大学化学化工学院     化学专业             本科/学士 


工作履历

2020.05-今               湖南大学化学化工学院     化学生物学系      副教授     

2018.03-2020.04     上海交通大学医学院         基础医学             博士后                           合作导师:杨朝勇教授

研究领域

DNA动态逻辑回路的仿生学应用,功能化DNA结构自组装的构建与生物学应用,生物分子的单分子荧光成像与运动分析,分子识别探针的构建与生物分析应用等。        

学术成果

[1]      Mingxu You*#, Yifan Lyu#, Da Han#, Liping Qiu, Qiaoling Liu, Tao Chen, Cuichen SamWu, Lu Peng, Liqin Zhang, Gang Bao and Weihong Tan*. DNA probes for monitoring dynamic and transient molecular encounters on live cell membranes. Nature Nanotechnology, 2017,12, 453-459. (co-first author, IF=37.49)

[2]      Yifan Lyu, Yian Guo, Ren Cai, Ruizi Peng, Chengyi Hong Xigao Chen, Weijia Hou, Xiaowei Li, Jie Tan, Yuxiu Zou, Xiaobing Zhang, Qiaoling Liu, Weihong Tan*, Spherically-directed synthesis and enhanced cellular internalization of metal-crosslinked DNA micelles, Chem, 2019, 5(4), 913-928, (IF=18.205)

[3]      Yifan Lyu, Cuichen Wu, Charles Heinke, Da Han*, Ren Cai, I-Ting Teng, Yuan Liu, Hui Liu, Xiaobing Zhang, Qiaoling Liu, and Weihong Tan*, Constructing Smart Protocells with Built-In DNA Computational Core to Eliminate Exogenous Challenge, Journal of the American Chemical Society, 2018, 140, 6912−6920. (IF=14.695)

[4]      Yifan Lv, Rong Hu, Guizhi Zhu, Xiaobing Zhang*, Lei Mei, Qiaoling Liu and Weihong Tan*. Preparation and Biomedical Applications of Programmable and Multifunctional DNA Nanoflowers. Nature Protocols, 2015, 10, 1508–1524. (IF=12.423)

[5]      Yifan Lyu, Ruizi Peng, Hui Liu, Hailan Kuai, Liuting Mo, Da Han, Juan Lia, and Weihong Tan*, Protocells programmed through artificial reaction networks, Chemical Science, 2020,11(3), 631-642. (IF=9.556)

[6]      Ting Fu#, Yifan Lyu#, Hui Liu, Ruizi Peng, Xiaobing Zhang, Mao Ye* and Weihong Tan*, DNA-Based Dynamic Reaction Networks, Trends in Biochemical Sciences, 2018, 43(7):547-560. (co-first author, IF=15.678)

[7]      Yifan Lyu, Guang Chen, Dihua Shangguan, Liqin Zhang, Shuo Wan, Yuan Wu, Hui Zhang, Lian Duan, Chao Liu, Mingxu You, Jie Wang* and Weihong Tan*. Generating Cell Targeting Aptamers for Nanotheranostics Using Cell-SELEX. Theranostics, 2016, 6(9): 1440-1453. (IF=8.063)

[8]      Yifan Lyu, I-Ting Teng, Liqin Zhang, Yian Guo, Ren Cai, Xiaobing Zhang, Liping Qiu*, and Weihong Tan*, Comprehensive Regression Model for Dissociation Equilibria of Cell-Specific Aptamers, Analytical Chemistry, 2018, 90(17), 10487−10493. (IF=6.35)

[9]      Yifan Lv, Liang Cui, Ruizi Peng, Zilong Zhao, Liping Qiu, Chen Jin, Xiao-Bing Zhang* Weihong Tan*. Entropy beacon: a hairpin-free DNA amplification strategy for efficient detection of nucleic acids. Analytical Chemistry, 2015, 87, 11714−11720. (IF=6.35)

[10]   Yifan Lv, Ruizi Peng, Yu Zhou, Xiaobing Zhang*, and Weihong Tan*. Catalytic self-assembly of a DNA dendritic complex for efficient gene silencing. Chemical Communications, 2016, 52, 1413-1415. (IF=6.16)

[11]   Xiangling Xiong#, Yifan Lv#, Tao Chen, Xiaobing Zhang, Kemin Wang, and Weihong Tan*. Nucleic Acid Aptamers for Living Cell Analysis. Annual Review of Analytical Chemistry, 2014, 7, 405-426. (co-first author, IF=8.756)